确定治疗窗口:亚洲患者创伤后和手术后疤痕的早期脉冲染料激光疗法与晚期脉冲染料激光疗法。

IF 2.2 3区 医学 Q2 DERMATOLOGY
Han-Yuan Chang, Bing-Qi Wu, Chang-Cheng Chang, Yu-Tsung Chen, Yen-Jen Wang
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引用次数: 0

摘要

研究目的这项回顾性研究评估了脉冲染料激光(PDL)治疗创伤性或术后疤痕的早期治疗组和晚期治疗组的疗效。研究旨在确定早期治疗和晚期治疗之间的临界值。此外,该研究还调查了可能影响伤口愈合结果的因素:回顾性审查了 2018 年 1 月至 2022 年 12 月期间在我院接受 PDL 治疗的 147 名患者的病历。纳入标准为因外伤或术后疤痕而接受 PDL 治疗的患者。在这些患者中,我们选择了愿意接受电话访谈或在预定时间再次就诊的患者。最终,52 名参与者被纳入了我们的研究。在电话访谈中,我们向所有参与者发放了一份标准化问卷,内容包括询问他们的病史、治疗经历以及患者和观察者疤痕评估量表中的患者部分。在登记的患者中,有 38 人接受了电话联系和访谈,其余 14 人接受了随访,并拍摄了当前皮肤状况的照片。从临床数据库中获得的治疗前照片和最近的随访照片由两名皮肤科医生使用温哥华疤痕量表和曼彻斯特疤痕量表进行盲法独立评分:52 名患者中,43 人(82.7%)治疗成功,反应良好。在反应良好的患者中,治疗开始一周与治疗后 MSS 和 VSS 之间的相关系数为 0.50(p 结论:PDL 是治疗疤痕的最佳方法:根据临床和患者的意见,在受伤后 10 周内使用 PDL 进行早期干预,在治疗外伤和术后疤痕方面取得了更好的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Defining the Treatment Window: Early Versus Late Pulsed Dye Laser Therapy for Posttraumatic and Surgical Scars in Asian Patients.

Objectives: This retrospective study evaluates the effectiveness of pulsed dye laser (PDL) treatment in early versus late treatment groups for traumatic or postoperative scars. The study aims to determine the threshold between early and late treatment. Additionally, it investigates factors that may influence wound healing outcomes.

Methods: The medical records of 147 patients who underwent PDL treatment at our institution between January 2018 and December 2022 were retrospectively reviewed. Inclusion criteria were patients receiving PDL treatment for traumatic or postoperative scars. Out of these patients, we selected those who were willing to receive telephone interviews or re-visit at a scheduled time. Eventually, 52 participants were included in our study. A standardized questionnaire was administered to all participants during telephone interviews, encompassing inquiries regarding their medical history, treatment experiences, and the patient component of the Patient and Observer Scar Assessment Scale. Among the enrolled patients, 38 were contacted and interviewed via telephone, while the remaining 14 patients attended follow-up visits where photographs of their current skin condition were captured. The pretreatment and latest follow-up photographs obtained from the clinical database were independently scored in a blinded manner by two dermatologist reviewers using both the Vancouver Scar Scale and the Manchester Scar Scale.

Results: Among the 52 patients, 43 (82.7%) were successfully treated with good response. The correlation coefficients between week-to-treatment initiation and posttreatment MSS and VSS among patients with good response were 0.50 (p < 0.001) and 0.46 (p = 0.002), respectively. Given these findings, we established a treatment initiation threshold of 10 weeks, distinguishing patients into early and late treatment groups. The early treatment group showed borderline significantly lower posttreatment MSS and VSS scores than the late treatment group (MSS: 7.5 ± 2.1 vs. 9.3 ± 2.5, p = 0.011; VSS: 2.8 ± 2.0 vs. 4.5 ± 2.3, p = 0.011). Furthermore, both MSS and VSS of posttreatment showed significantly greater improvement in the early treatment group (4.4 ± 1.6 vs. 3.2 ± 1.9; p = 0.03 and 3.8 ± 1.8 vs. 2.8 ± 1.4; p = 0.04).

Conclusions: Early intervention using a PDL within 10 weeks post-injury achieved better outcomes in treating traumatic and postoperative scars based on both clinical and patient opinions.

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来源期刊
CiteScore
5.40
自引率
12.50%
发文量
119
审稿时长
1 months
期刊介绍: Lasers in Surgery and Medicine publishes the highest quality research and clinical manuscripts in areas relating to the use of lasers in medicine and biology. The journal publishes basic and clinical studies on the therapeutic and diagnostic use of lasers in all the surgical and medical specialties. Contributions regarding clinical trials, new therapeutic techniques or instrumentation, laser biophysics and bioengineering, photobiology and photochemistry, outcomes research, cost-effectiveness, and other aspects of biomedicine are welcome. Using a process of rigorous yet rapid review of submitted manuscripts, findings of high scientific and medical interest are published with a minimum delay.
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