1997-2023年在北美动物园发现的圈养吉拉怪兽（heloderma suspectum）胃肠道腺癌。

IF 0.7 4区农林科学 Q3 VETERINARY SCIENCES

Journal of Zoo and Wildlife Medicine Pub Date : 2024-09-01 DOI:10.1638/2023-0130

Kali Holder, Nina Katzenstein

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引用次数: 0

摘要

有关吉拉怪兽（Heloderma suspectum）肿瘤的调查并不常见，有关该物种肿瘤发病率和类型的文献也很少。尤其是胃肠道腺癌（GTA），在吉拉怪中仅有两次报道，一次发生在小肠，一次发生在结肠。在这个病例系列中，史密森尼国家动物园和保护生物学研究所（SNZCBI）的病理部门在 26 年（1997-2023 年）的时间里发现 50%（7/14）的吉拉怪兽患有肠道和/或结肠腺癌。该动物园报告的 GTA 发生率可能代表了多因素病因，包括标本的老年化、慢性炎症、胃肠道感染，以及/或由于该动物园以前的报告而增加了对该疾病的认识。提高对该物种 GTA 的认识可能会提高对该疾病的识别率。

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GASTROINTESTINAL TRACT ADENOCARCINOMA IDENTIFIED IN CAPTIVE GILA MONSTERS (HELODERMA SUSPECTUM) IN A NORTH AMERICAN ZOO, 1997-2023.

Neoplasia in the Gila monster (Heloderma suspectum) is not commonly investigated, and literature regarding the prevalence and type of neoplasms that affect this species is sparse. Gastrointestinal tract adenocarcinoma (GTA) in particular has only been reported twice in Gila monsters, once in the small intestine and once in the colon. In this case series, 50% (7/14) of the Gila monsters presented to the pathology service at Smithsonian's National Zoo and Conservation Biology Institute (SNZCBI) over the span of 26 yr (1997-2023) were found to have intestinal and/or colonic adenocarcinoma. The frequency of GTA reported in this collection likely represents a multifactorial etiology including geriatric age of specimens, chronic inflammation, gastrointestinal tract infection, and/or increased cognizance of the disease because of previous reports within the collection. An increased awareness of GTA in this species may lead to improved recognition of the disease.

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来源期刊

Journal of Zoo and Wildlife Medicine 农林科学-兽医学

CiteScore

1.70

自引率

14.30%

发文量

审稿时长

9-24 weeks

期刊介绍： The Journal of Zoo and Wildlife Medicine (JZWM) is considered one of the major sources of information on the biology and veterinary aspects in the field. It stems from the founding premise of AAZV to share zoo animal medicine experiences. The Journal evolved from the long history of members producing case reports and the increased publication of free-ranging wildlife papers. The Journal accepts manuscripts of original research findings, case reports in the field of veterinary medicine dealing with captive and free-ranging wild animals, brief communications regarding clinical or research observations that may warrant publication. It also publishes and encourages submission of relevant editorials, reviews, special reports, clinical challenges, abstracts of selected articles and book reviews. The Journal is published quarterly, is peer reviewed, is indexed by the major abstracting services, and is international in scope and distribution. Areas of interest include clinical medicine, surgery, anatomy, radiology, physiology, reproduction, nutrition, parasitology, microbiology, immunology, pathology (including infectious diseases and clinical pathology), toxicology, pharmacology, and epidemiology.