丁吗啡诺-咪达唑仑-美托咪定方案对小鼷鹿短程手术的评估。

IF 0.7 4区 农林科学 Q3 VETERINARY SCIENCES
Guillaume Douay, Yirui Heng, Abraham Mathew
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引用次数: 0

摘要

对20只小鼷鹿进行了丁吗啡-咪达唑仑-美托咪定(BMidM)组合麻醉,以评估该方案在该属动物的短程手术中的有效性,其中10只为雄性,10只为雌性。动物通过手部肌肉注射 BMidM(分别为 0.32、0.06 和 0.15 毫克/千克)。当动物达到持续 30 分钟(12-60 分钟不等)的工作麻醉深度后,记录其生理变量。手术结束后,分别用阿替帕唑(0.75 毫克/千克)和纳曲酮(0.3 毫克/千克)肌肉注射拮抗美托咪定和丁吗啡诺。诱导和恢复时间分别为 9.4 ± 4.0 分钟和 10.2 ± 4.1 分钟。五只动物需要通过面罩补充异氟醚才能达到轻度麻醉。比较了不同性别动物达到不同麻醉阶段所需的时间。雄性和雌性动物达到不同麻醉阶段的时间没有差异,但达到活动阶段所需的时间不同,雌性动物在注射拮抗剂后站立所需的时间明显更长(11.8 分钟对雄性动物的 7.8 分钟)(P = 0.02)。在整个过程中,雌雄动物的心率、呼吸频率、直肠温度和外周血血红蛋白氧饱和度相似且稳定。在测试的剂量下,BMidM 是一种可靠、安全的方案,适用于对小鼷鹿进行短时间的微创手术,诱导快速,恢复顺利,无并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
EVALUATION OF A BUTORPHANOL-MIDAZOLAM-MEDETOMIDINE PROTOCOL FOR SHORT PROCEDURES IN LESSER CHEVROTAINS (TRAGULUS SP.).

Twenty lesser chevrotains (Tragulus sp.), 10 males and 10 females, were anesthetized with a combination of butorphanol-midazolam-medetomidine (BMidM), to assess the efficacy of this protocol for short procedures in this genus. The animals received BMidM (0.32, 0.06, 0.15 mg/kg, respectively) intramuscularly via hand injection. Physiological variables were recorded once the animals reached a working depth of anesthesia that lasted 30 min (range 12-60 min). At the end of the procedure, medetomidine and butorphanol were antagonized with atipamezole (0.75 mg/kg) and naltrexone (0.3 mg/kg) intramuscularly, respectively. Induction and recovery were 9.4 ± 4.0 min and 10.2 ± 4.1 min, respectively. Supplementation with isoflurane via face mask was required in five animals to reach light anesthesia. Times to reach the various stages of anesthesia were compared between sexes. There was no difference between males and females reaching the different stages of anesthesia, except for the time required to reach the ambulatory stage, in which females took a significantly longer time (11.8 min vs 7.8 min for the males) to stand after the injection of the antagonists (P = 0.02). Heart rate, respiratory rate, rectal temperature, and peripheral hemoglobin oxygen saturation were similar between sexes and stable throughout the procedure. At the dosage tested BMidM was a reliable and safe protocol for short, minimally invasive procedures in lesser chevrotains with a fast induction and smooth recovery without complications.

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来源期刊
Journal of Zoo and Wildlife Medicine
Journal of Zoo and Wildlife Medicine 农林科学-兽医学
CiteScore
1.70
自引率
14.30%
发文量
74
审稿时长
9-24 weeks
期刊介绍: The Journal of Zoo and Wildlife Medicine (JZWM) is considered one of the major sources of information on the biology and veterinary aspects in the field. It stems from the founding premise of AAZV to share zoo animal medicine experiences. The Journal evolved from the long history of members producing case reports and the increased publication of free-ranging wildlife papers. The Journal accepts manuscripts of original research findings, case reports in the field of veterinary medicine dealing with captive and free-ranging wild animals, brief communications regarding clinical or research observations that may warrant publication. It also publishes and encourages submission of relevant editorials, reviews, special reports, clinical challenges, abstracts of selected articles and book reviews. The Journal is published quarterly, is peer reviewed, is indexed by the major abstracting services, and is international in scope and distribution. Areas of interest include clinical medicine, surgery, anatomy, radiology, physiology, reproduction, nutrition, parasitology, microbiology, immunology, pathology (including infectious diseases and clinical pathology), toxicology, pharmacology, and epidemiology.
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