监测步行对心肌灌注成像中心外膜肠活动的影响

IF 1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Anja Strok, Maja Dolenc Novak, Barbara Guzic Salobir, Monika Stalc, Katja Zaletel
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引用次数: 0

摘要

为了减少心肌灌注成像(MPI)中的胃肠道活动干扰,已经使用了多种技术;但是,这些方法产生的结果并不一致。本研究的目的是探讨在使用 SPECT 进行药物应激 99mTc-tetrofosmin MPI 时,监控行走(一种以前未曾探索过的技术)在减少膈下活动相关伪影以提高整体图像质量方面的功效。研究方法研究对象包括接受药物应激 MPI 的患者。他们在注射放射性示踪剂后立即获得计步器,并被随机分为 A 组(要求在成像前至少步行 1000 步)和 B 组(没有关于步行的具体说明)。对重建的 SPECT 图像进行目测评估。膈下示踪剂活动的中度和重度水平被认为与扫描结果的判读有关。此外,还对原始平面图像上的心肌和腹部活动进行了半定量评估,并计算了心肌与腹部的平均计数比。结果我们共招募了 199 名患者(A 组 95 名,B 组 104 名)。两组患者的临床特征无明显差异。A 组患者比 B 组患者走的步数多(P < 0.001),但两组患者接受扫描的比例没有差异(P = 0.41)。此外,两组间相关膈下活动的比例也没有差异(P = 0.91)。步骤数对接受率没有影响(P = 0.29)。结论在药物应激和采集之间的等待期间,行走的步数越多,越不会影响膈下活动相关伪影或药物应激后接受扫描的比例。不过,使用计步器和明确的指导可促使患者在等待成像时步行。需要进行更大规模的研究,比较高步数组和静坐对照组,以评估步行对 MPI 胃肠道伪影的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effect of Monitored Walking on Extracardiac Intestinal Activity in Myocardial Perfusion Imaging.

Various techniques have been used in attempts to reduce interfering gastrointestinal activity in myocardial perfusion imaging (MPI); however, these approaches have yielded inconsistent results. The goal of this study was to investigate the efficacy of monitored walking, a previously unexplored technique, in reducing subdiaphragmatic activity-related artifacts during pharmacologic stress 99mTc-tetrofosmin MPI with SPECT to improve the overall image quality. Methods: The study included patients who underwent MPI with pharmacologic stress. They were given a step counter immediately after the radiotracer injection and were randomized into a group A, with a request to walk at least 1,000 steps before imaging, and a group B, with no specific instructions about walking. The reconstructed SPECT images were assessed visually. Moderate and severe levels of subdiaphragmatic tracer activity were considered relevant for the interpretation of the scans. Additionally, myocardial and abdominal activity was semiquantitatively assessed on raw planar images, and the mean myocardium-to-abdomen count ratios were calculated. Results: We enrolled 199 patients (95 patients in group A and 104 patients in group B). Clinical characteristics did not differ significantly between the 2 groups. Patients in group A walked more steps than patients in group B (P < 0.001), but there were no differences in the proportion of accepted scans between the 2 groups (P = 0.41). Additionally, there were no differences in the proportion of relevant subdiaphragmatic activity between the groups (P = 0.91). The number of steps did not impact the acceptance rate (P = 0.29). Conclusion: A higher number of steps walked during the waiting period between pharmacologic stress and acquisition does not affect subdiaphragmatic activity-related artifacts or the proportion of accepted scans after pharmacologic stress. However, pedometer use and clear instructions motivate patients to walk while awaiting imaging. Larger studies are required to compare a higher-step-count group with a sedentary control group to assess the influence of walking on gastrointestinal artifacts in MPI.

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来源期刊
Journal of nuclear medicine technology
Journal of nuclear medicine technology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.90
自引率
15.40%
发文量
57
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