下颌骨动脉瘤性骨囊肿的强力霉素硬化疗法：简要临床研究。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-23 DOI:10.1097/SCS.0000000000010697

Megan N Wong, James W Murakami

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引用次数: 0

摘要

动脉瘤性骨囊肿（ABC）是一种良性骨肿瘤，通常发生在儿童身上。由于下颌骨动脉瘤囊肿的解剖位置敏感，且对功能和外观都有影响，因此很难通过手术治疗。本报告介绍了在图像引导下采用经皮多西环素硬化疗法成功治疗的3例下颌骨ABC小儿患者。前两名患者表现为疼痛和肿胀，而第三名患者是偶然被诊断出来的。硬化疗法是 1 号和 2 号病例的唯一治疗方法，而 3 号病例则是在之前的手术后复发后进行的硬化疗法。所有 3 名患者的临床症状均已缓解，长期随访显示骨愈合稳定。没有出现功能性或外观上的并发症。强力霉素硬化疗法是治疗原发性和复发性下颌骨ABC的一种安全可行的方法。

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Doxycycline Sclerotherapy of Mandibular Aneurysmal Bone Cysts: A Brief Clinical Study.

Aneurysmal bone cysts (ABCs) are benign bone tumors typically affecting children. Mandibular ABCs can be difficult to treat surgically, given their sensitive anatomic location and functional and cosmetic impacts. This report presents 3 pediatric patients with mandibular ABCs successfully treated with image-guided percutaneous doxycycline sclerotherapy. The first 2 patients presented with pain and swelling, whereas the third was diagnosed incidentally. Sclerotherapy was the sole treatment for cases 1 and 2, whereas case 3 had sclerotherapy after recurrence following prior surgeries. In all 3 patients, clinical symptoms resolved, and stable bone healing was documented on long-term follow-up. There were no functional or cosmetic complications. Doxycycline sclerotherapy is a safe and viable treatment for primary and recurrent mandibular ABCs.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.