眼科粘弹剂的物理特性、临床应用和副作用。

IF 1.2 Q3 OPHTHALMOLOGY
Journal of Current Ophthalmology Pub Date : 2024-08-10 eCollection Date: 2023-10-01 DOI:10.4103/joco.joco_178_23
Mehrdad Mohammadpour, Hassan Asadigandomani, Mehdi Aminizade, Saeed Raeisi
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引用次数: 0

摘要

目的:解释眼科粘弹性设备(OVD)的物理特性,包括其结构单元、最佳特性、现有粘弹性材料、临床应用和潜在副作用:本文是一篇关于眼科粘弹性设备的叙述性综述。在 PubMed、Google Scholar 和 Scopus 数据库中进行了文献综述。结果:我们纳入了 2010 年以来的 42 篇文章,讨论了 OVD 的物理特性、临床应用、OVD 商业产品及其并发症:我们收录了 2010 年以来的 42 篇文章,讨论了物理特性、理想 OVD 的属性、常见 OVD 的结构单元、OVD 商业产品、临床应用以及 OVD 的并发症:如今,粘弹性材料因其卓越的特性在眼内手术中发挥着独特而关键的作用。这些材料可以保护内皮和上皮,维持前房深度,控制眼内出血,方便组织处理,并有助于眼内晶状体置入。目前,美国市场上流行的粘弹性材料有 12 种,包括 7 种透明质酸钠衍生物(Healon、Healon-Greater Viscosity、Healon-5、Amvisc、Amvisc Plus、Advanced Medical Optics Vitrax 和 Provisc)、2 种 2% 羟丙基甲基纤维素衍生物(OcuCoat 和 Cellugel)以及 3 种透明质酸钠和硫酸软骨素的组合(Viscoat、DisCoVisc 和 DuoVisc)。尽管每年都有新的粘弹性材料问世,但没有一种材料能涵盖所有所需的特性。外科医生必须根据手术条件和患者要求选择和使用合适的粘弹性材料。材料开发的进步以及对物理性质和临床应用的了解不断完善着粘弹性材料的选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Physical Characteristics, Clinical Application, and Side Effects of Viscoelastics in Ophthalmology.

Purpose: To explain the physical properties of ophthalmic viscoelastic devices (OVDs), covering their structural units, optimal features, existing viscoelastic materials, clinical applications, and potential side effects.

Methods: This is a narrative review on the OVDs. A literature review was conducted in PubMed, Google Scholar, and Scopus databases. Studies that investigated physical characteristics, clinical applications, OVD commercial products, and their complications were included.

Results: We included 42 articles from 2010 and discussed physical characteristics, properties of a desirable OVD, structural units of common OVDs, OVD commercial products, clinical applications, and also complications of OVDs.

Conclusions: Today, viscoelastics hold a distinct and crucial role in intraocular surgery due to their remarkable properties. These materials safeguard the endothelium and epithelium, uphold anterior chamber depth, manage intraocular bleeding, ease tissue handling, and aid intraocular lens placement. Currently, the American market features 12 prevalent viscoelastic types, including 7 sodium hyaluronate derivatives (Healon, Healon-Greater Viscosity, Healon-5, Amvisc, Amvisc Plus, Advanced Medical Optics Vitrax, and Provisc), 2 hydroxypropyl methylcellulose 2% derivatives (OcuCoat and Cellugel), and 3 combinations of sodium hyaluronate and chondroitin sulfate (Viscoat, DisCoVisc, and DuoVisc). Despite the introduction of new viscoelastic materials annually, no single material encompasses all desired properties. Surgeons must select and employ suitable viscoelastics based on surgical conditions and patient requirements. Advancements in material development and understanding of physical properties and clinical applications continue to refine viscoelastic selection.

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来源期刊
CiteScore
2.50
自引率
6.70%
发文量
45
审稿时长
8 weeks
期刊介绍: Peer Review under the responsibility of Iranian Society of Ophthalmology Journal of Current Ophthalmology, the official publication of the Iranian Society of Ophthalmology, is a peer-reviewed, open-access, scientific journal that welcomes high quality original articles related to vision science and all fields of ophthalmology. Journal of Current Ophthalmology is the continuum of Iranian Journal of Ophthalmology published since 1969.
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