龈沟液中瘦素浓度与正畸牙齿移动速度的相关性--一项前瞻性研究

Q3 Dentistry
Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-09-14 DOI:10.4103/ijdr.ijdr_714_22
Adel Alharbi, Rinkee Mohanty, Geetika Tomer, Atul Anand Bajoria, Azhar Mohammed, Prashant Babaji
{"title":"龈沟液中瘦素浓度与正畸牙齿移动速度的相关性--一项前瞻性研究","authors":"Adel Alharbi, Rinkee Mohanty, Geetika Tomer, Atul Anand Bajoria, Azhar Mohammed, Prashant Babaji","doi":"10.4103/ijdr.ijdr_714_22","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The evaluation of genetic markers in the gingival crevicular fluid (GCF) and their connection to tooth movement can be helpful.</p><p><strong>Aim: </strong>The objective of this research is to assess the relationship involving leptin levels and orthodontic tooth movement (OTM).</p><p><strong>Study setting and design: </strong>Thirty individuals reporting to the Department of Orthodontics participated in an observational prospective study.</p><p><strong>Material and method: </strong>Thirty orthodontic patients (15 male and 15 female) were included in the current study. The association of leptin concentration (GCF) was measured before and after orthodontic force was applied to move the mesially impacted canine distally (tooth movement distance on dental cast).</p><p><strong>Statistical analysis: </strong>With the help of SPSS software version 21, the data were statistically examined using the \" t \" test, one-way ANOVA, and Bonferroni correction in Chicago. The average degree of tooth movement was calculated using Pearson's correlation coefficient, and it was connected to the average leptin levels.</p><p><strong>Results: </strong>Average leptin levels in GCF elevated from baseline (T0, 285.315 picograms/micro litre) to 1 h after force application (T1, 384.683 pg/μL), then raised to a maximum at after 24 h (T2, 927.64 pg/μL), and decreased to the least amount after 15 days (T3, 29.26 pg/μL) and another time increase after two months (242.31 pg/μL). The degree of OTM was significantly correlated with the levels of leptin.</p><p><strong>Conclusion: </strong>While OTM was occurring, a biphasic fluctuation in the leptin level was noted. The amount of tooth movement was significantly correlated with the GCF leptin level.</p>","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Correlation of Leptin Concentration in Gingival Crevicular Fluid on the Rate of Orthodontic Tooth Movement - A Prospective Study.\",\"authors\":\"Adel Alharbi, Rinkee Mohanty, Geetika Tomer, Atul Anand Bajoria, Azhar Mohammed, Prashant Babaji\",\"doi\":\"10.4103/ijdr.ijdr_714_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The evaluation of genetic markers in the gingival crevicular fluid (GCF) and their connection to tooth movement can be helpful.</p><p><strong>Aim: </strong>The objective of this research is to assess the relationship involving leptin levels and orthodontic tooth movement (OTM).</p><p><strong>Study setting and design: </strong>Thirty individuals reporting to the Department of Orthodontics participated in an observational prospective study.</p><p><strong>Material and method: </strong>Thirty orthodontic patients (15 male and 15 female) were included in the current study. The association of leptin concentration (GCF) was measured before and after orthodontic force was applied to move the mesially impacted canine distally (tooth movement distance on dental cast).</p><p><strong>Statistical analysis: </strong>With the help of SPSS software version 21, the data were statistically examined using the \\\" t \\\" test, one-way ANOVA, and Bonferroni correction in Chicago. The average degree of tooth movement was calculated using Pearson's correlation coefficient, and it was connected to the average leptin levels.</p><p><strong>Results: </strong>Average leptin levels in GCF elevated from baseline (T0, 285.315 picograms/micro litre) to 1 h after force application (T1, 384.683 pg/μL), then raised to a maximum at after 24 h (T2, 927.64 pg/μL), and decreased to the least amount after 15 days (T3, 29.26 pg/μL) and another time increase after two months (242.31 pg/μL). The degree of OTM was significantly correlated with the levels of leptin.</p><p><strong>Conclusion: </strong>While OTM was occurring, a biphasic fluctuation in the leptin level was noted. The amount of tooth movement was significantly correlated with the GCF leptin level.</p>\",\"PeriodicalId\":13311,\"journal\":{\"name\":\"Indian Journal of Dental Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Dental Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/ijdr.ijdr_714_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/9/14 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"Dentistry\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Dental Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ijdr.ijdr_714_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/14 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Dentistry","Score":null,"Total":0}
引用次数: 0

摘要

背景:目的:本研究的目的是评估瘦素水平与正畸牙齿移动(OTM)之间的关系:30名向正畸科报到的患者参与了一项前瞻性观察研究:本次研究共纳入 30 名正畸患者(15 名男性和 15 名女性)。在施加正畸力将中侧受影响的犬齿向远端移动(牙齿铸模上的牙齿移动距离)之前和之后,测量瘦素浓度(GCF)的相关性:在 SPSS 软件 21 版的帮助下,使用 "t "检验、单因素方差分析和芝加哥的 Bonferroni 校正对数据进行统计分析。使用皮尔逊相关系数计算牙齿移动的平均程度,并将其与瘦素的平均水平联系起来:结果:GCF中瘦素的平均水平从基线(T0,285.315皮克/微升)升高到施力后1小时(T1,384.683皮克/微升),然后在24小时后升高到最大值(T2,927.64皮克/微升),15天后降至最低值(T3,29.26皮克/微升),两个月后再次升高(242.31皮克/微升)。OTM 的程度与瘦素水平明显相关:结论:OTM 发生时,瘦素水平呈双相波动。结论:OTM发生时,瘦素水平呈双相波动,牙齿移动量与GCF瘦素水平有明显相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correlation of Leptin Concentration in Gingival Crevicular Fluid on the Rate of Orthodontic Tooth Movement - A Prospective Study.

Background: The evaluation of genetic markers in the gingival crevicular fluid (GCF) and their connection to tooth movement can be helpful.

Aim: The objective of this research is to assess the relationship involving leptin levels and orthodontic tooth movement (OTM).

Study setting and design: Thirty individuals reporting to the Department of Orthodontics participated in an observational prospective study.

Material and method: Thirty orthodontic patients (15 male and 15 female) were included in the current study. The association of leptin concentration (GCF) was measured before and after orthodontic force was applied to move the mesially impacted canine distally (tooth movement distance on dental cast).

Statistical analysis: With the help of SPSS software version 21, the data were statistically examined using the " t " test, one-way ANOVA, and Bonferroni correction in Chicago. The average degree of tooth movement was calculated using Pearson's correlation coefficient, and it was connected to the average leptin levels.

Results: Average leptin levels in GCF elevated from baseline (T0, 285.315 picograms/micro litre) to 1 h after force application (T1, 384.683 pg/μL), then raised to a maximum at after 24 h (T2, 927.64 pg/μL), and decreased to the least amount after 15 days (T3, 29.26 pg/μL) and another time increase after two months (242.31 pg/μL). The degree of OTM was significantly correlated with the levels of leptin.

Conclusion: While OTM was occurring, a biphasic fluctuation in the leptin level was noted. The amount of tooth movement was significantly correlated with the GCF leptin level.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Indian Journal of Dental Research
Indian Journal of Dental Research Dentistry-Dentistry (all)
CiteScore
1.80
自引率
0.00%
发文量
80
审稿时长
38 weeks
期刊介绍: Indian Journal of Dental Research (IJDR) is the official publication of the Indian Society for Dental Research (ISDR), India section of the International Association for Dental Research (IADR), published quarterly. IJDR publishes scientific papers on well designed and controlled original research involving orodental sciences. Papers may also include reports on unusual and interesting case presentations and invited review papers on significant topics.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信