原发性皮肤黑色素瘤

IF 2.3 4区 医学 Q2 DERMATOLOGY
Jennifer Y Wang, Susan M Swetter
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引用次数: 0

摘要

原发性真皮黑色素瘤(PDM)是黑色素瘤的一种罕见亚型,估计发病率低于 1%。原发性真皮黑色素瘤完全发生在真皮或皮下,由于与上覆的表皮没有联系,组织病理学上类似于黑色素瘤的皮肤转移。全面的病史和检查(包括转移性疾病的影像学评估)会发现患者以前没有原发性皮肤黑色素瘤或转移性黑色素瘤的病史或并发症。尽管其组织病理学与黑色素瘤转移相似,但 PDM 的预后却出乎意料地良好。本综述将讨论作为黑色素瘤一个独特亚型的 PDM 的临床和组织病理学特征,以及目前的临床分期和管理方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Primary dermal melanoma.

Primary dermal melanoma (PDM) is a rare subtype of melanoma with an estimated incidence of <1%. PDM manifests entirely in the dermis or subcutis and histopathologically mimics cutaneous melanoma metastasis due to its lack of connection to the overlying epidermis. A thorough history and examination, including imaging evaluation for metastatic disease, reveals no prior history or concurrent primary cutaneous or metastatic melanoma lesion. Despite its histopathologic similarities to melanoma metastasis, PDM is associated with an unexpectedly favorable prognosis. This review discusses the clinical and histopathologic features of PDM as a distinct subtype of melanoma, as well as the current approach to clinical staging and management.

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来源期刊
Clinics in dermatology
Clinics in dermatology 医学-皮肤病学
CiteScore
4.60
自引率
7.40%
发文量
106
审稿时长
3 days
期刊介绍: Clinics in Dermatology brings you the most practical and comprehensive information on the treatment and care of skin disorders. Each issue features a Guest Editor and is devoted to a single timely topic relating to clinical dermatology. Clinics in Dermatology provides information that is... • Clinically oriented -- from evaluation to treatment, Clinics in Dermatology covers what is most relevant to you in your practice. • Authoritative -- world-renowned experts in the field assure the high-quality and currency of each issue by reporting on their areas of expertise. • Well-illustrated -- each issue is complete with photos, drawings and diagrams to illustrate points and demonstrate techniques.
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