Raymond L Barnhill, Michael W Piepkorn, Lyn M Duncan, Stevan Knezevich, Joann G Elmore, David E Elder
{"title":"黑色素细胞病变的 MPATH-Dx 2.0 版本模式:用于标准化诊断报告的强大工具。","authors":"Raymond L Barnhill, Michael W Piepkorn, Lyn M Duncan, Stevan Knezevich, Joann G Elmore, David E Elder","doi":"10.1016/j.clindermatol.2024.09.007","DOIUrl":null,"url":null,"abstract":"<p><p>The new revised MPATH-Dx (version 2.0) reporting schema for melanocytic lesions is presented. Principal changes include the simplification of the previous five-class version 1.0 to a four-class hierarchy of melanocytic lesions to improve diagnostic agreement and to provide more explicit guidance for the management of patients. Version 2.0 also has clearly defined histopathologic criteria for classification of class I and II lesions, which are now designated as low-grade (mild-to-moderate) atypia and high-grade (high-end moderate-to-severe) atypia, respectively. This new revised schema also includes specific provisions for the less common World Health Organization pathways to melanoma, provides guidance for classifying \"intermediate\" class II tumors (melanocytomas), and recognizes a subset of pT1a melanomas with very low risk and possible eventual reclassification as a neoplasm falling short of fully evolved melanoma.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"MPATH-Dx version 2.0 schema for melanocytic lesions: A robust tool for standardized diagnostic reporting.\",\"authors\":\"Raymond L Barnhill, Michael W Piepkorn, Lyn M Duncan, Stevan Knezevich, Joann G Elmore, David E Elder\",\"doi\":\"10.1016/j.clindermatol.2024.09.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The new revised MPATH-Dx (version 2.0) reporting schema for melanocytic lesions is presented. Principal changes include the simplification of the previous five-class version 1.0 to a four-class hierarchy of melanocytic lesions to improve diagnostic agreement and to provide more explicit guidance for the management of patients. Version 2.0 also has clearly defined histopathologic criteria for classification of class I and II lesions, which are now designated as low-grade (mild-to-moderate) atypia and high-grade (high-end moderate-to-severe) atypia, respectively. This new revised schema also includes specific provisions for the less common World Health Organization pathways to melanoma, provides guidance for classifying \\\"intermediate\\\" class II tumors (melanocytomas), and recognizes a subset of pT1a melanomas with very low risk and possible eventual reclassification as a neoplasm falling short of fully evolved melanoma.</p>\",\"PeriodicalId\":10358,\"journal\":{\"name\":\"Clinics in dermatology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-09-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinics in dermatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.clindermatol.2024.09.007\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinics in dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.clindermatol.2024.09.007","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
本文介绍了新修订的 MPATH-Dx(2.0 版)黑色素细胞病变报告模式。主要的变化包括将 1.0 版的五级黑色素细胞病变简化为四级,以提高诊断一致性,并为患者的治疗提供更明确的指导。2.0 版还明确界定了 I 级和 II 级病变的组织病理学分类标准,现在分别称为低度(轻度至中度)不典型和高度(高端中度至重度)不典型。这一新修订的模式还包括针对世卫组织较少见的黑色素瘤发病途径的具体规定,为 "中级 "II 类肿瘤(黑色素细胞瘤)的分类提供了指导,并确认了风险极低的 pT1a 黑色素瘤亚群,其最终可能被重新分类为未完全演变为黑色素瘤的肿瘤。
MPATH-Dx version 2.0 schema for melanocytic lesions: A robust tool for standardized diagnostic reporting.
The new revised MPATH-Dx (version 2.0) reporting schema for melanocytic lesions is presented. Principal changes include the simplification of the previous five-class version 1.0 to a four-class hierarchy of melanocytic lesions to improve diagnostic agreement and to provide more explicit guidance for the management of patients. Version 2.0 also has clearly defined histopathologic criteria for classification of class I and II lesions, which are now designated as low-grade (mild-to-moderate) atypia and high-grade (high-end moderate-to-severe) atypia, respectively. This new revised schema also includes specific provisions for the less common World Health Organization pathways to melanoma, provides guidance for classifying "intermediate" class II tumors (melanocytomas), and recognizes a subset of pT1a melanomas with very low risk and possible eventual reclassification as a neoplasm falling short of fully evolved melanoma.
期刊介绍:
Clinics in Dermatology brings you the most practical and comprehensive information on the treatment and care of skin disorders. Each issue features a Guest Editor and is devoted to a single timely topic relating to clinical dermatology.
Clinics in Dermatology provides information that is...
• Clinically oriented -- from evaluation to treatment, Clinics in Dermatology covers what is most relevant to you in your practice.
• Authoritative -- world-renowned experts in the field assure the high-quality and currency of each issue by reporting on their areas of expertise.
• Well-illustrated -- each issue is complete with photos, drawings and diagrams to illustrate points and demonstrate techniques.