分组测试数据回归模型中的后选择推断。

IF 1.4 4区 数学 Q3 BIOLOGY
Biometrics Pub Date : 2024-07-01 DOI:10.1093/biomtc/ujae101
Qinyan Shen, Karl Gregory, Xianzheng Huang
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引用次数: 0

摘要

我们开发了一种在逻辑回归中选择变量后进行有效推断的方法,这种方法适用于部分观察到反应的情况,即观察到一组容易出错的测试结果而不是反应的真实值。为了选择重要的协变量,同时考虑响应数据中的缺失信息,我们采用期望最大化算法来计算受 LASSO 惩罚的最大似然估计值。在变量选择之后,我们根据多面体(polyhedral)lemma 扩展了选择后推断方法,从而对所选协变量的影响进行推断。大量模拟研究的经验证据表明,与使用相同数据进行变量选择和推断而不对变量选择进行调整的天真推断方法相比,我们的后选择推断结果更加可靠。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Post-selection inference in regression models for group testing data.

We develop a methodology for valid inference after variable selection in logistic regression when the responses are partially observed, that is, when one observes a set of error-prone testing outcomes instead of the true values of the responses. Aiming at selecting important covariates while accounting for missing information in the response data, we apply the expectation-maximization algorithm to compute maximum likelihood estimators subject to LASSO penalization. Subsequent to variable selection, we make inferences on the selected covariate effects by extending post-selection inference methodology based on the polyhedral lemma. Empirical evidence from our extensive simulation study suggests that our post-selection inference results are more reliable than those from naive inference methods that use the same data to perform variable selection and inference without adjusting for variable selection.

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来源期刊
Biometrics
Biometrics 生物-生物学
CiteScore
2.70
自引率
5.30%
发文量
178
审稿时长
4-8 weeks
期刊介绍: The International Biometric Society is an international society promoting the development and application of statistical and mathematical theory and methods in the biosciences, including agriculture, biomedical science and public health, ecology, environmental sciences, forestry, and allied disciplines. The Society welcomes as members statisticians, mathematicians, biological scientists, and others devoted to interdisciplinary efforts in advancing the collection and interpretation of information in the biosciences. The Society sponsors the biennial International Biometric Conference, held in sites throughout the world; through its National Groups and Regions, it also Society sponsors regional and local meetings.
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