{"title":"不对称 2,4-二芳基取代和 3-溴-2-(4-溴烷氧基)衍生吡喃香豆素的合成。","authors":"Velu Saravanan, Pin-Hui Lin, Ding-Yah Yang","doi":"10.1039/d4ob01353k","DOIUrl":null,"url":null,"abstract":"<p><p>A series of unsymmetrical 2,4-disubstituted pyranocoumarins and 3-bromo-2-(4-bromoalkoxy)-derived pyranocoumarins were synthesized <i>via</i> the palladium-catalyzed C-H arylation of 4-phenyl-4<i>H</i>,5<i>H</i>-pyrano[3,2-<i>c</i>]chromen-5-ones with aryl iodide and the three-component reaction of 4-phenyl-4<i>H</i>,5<i>H</i>-pyrano[3,2-<i>c</i>]chromen-5-one with bromine and cyclic ether, respectively.</p>","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis of unsymmetrical 2,4-diaryl substituted and 3-bromo-2-(4-bromoalkoxy)-derived pyranocoumarins.\",\"authors\":\"Velu Saravanan, Pin-Hui Lin, Ding-Yah Yang\",\"doi\":\"10.1039/d4ob01353k\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A series of unsymmetrical 2,4-disubstituted pyranocoumarins and 3-bromo-2-(4-bromoalkoxy)-derived pyranocoumarins were synthesized <i>via</i> the palladium-catalyzed C-H arylation of 4-phenyl-4<i>H</i>,5<i>H</i>-pyrano[3,2-<i>c</i>]chromen-5-ones with aryl iodide and the three-component reaction of 4-phenyl-4<i>H</i>,5<i>H</i>-pyrano[3,2-<i>c</i>]chromen-5-one with bromine and cyclic ether, respectively.</p>\",\"PeriodicalId\":96,\"journal\":{\"name\":\"Organic & Biomolecular Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2024-09-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Organic & Biomolecular Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1039/d4ob01353k\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic & Biomolecular Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4ob01353k","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Synthesis of unsymmetrical 2,4-diaryl substituted and 3-bromo-2-(4-bromoalkoxy)-derived pyranocoumarins.
A series of unsymmetrical 2,4-disubstituted pyranocoumarins and 3-bromo-2-(4-bromoalkoxy)-derived pyranocoumarins were synthesized via the palladium-catalyzed C-H arylation of 4-phenyl-4H,5H-pyrano[3,2-c]chromen-5-ones with aryl iodide and the three-component reaction of 4-phenyl-4H,5H-pyrano[3,2-c]chromen-5-one with bromine and cyclic ether, respectively.