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IRF8 是小胶质细胞染色质景观的持久设计师

IF 27.7 1区 医学 Q1 IMMUNOLOGY
Nature Immunology Pub Date : 2024-09-23 DOI:10.1038/s41590-024-01965-z
Maximilian Frosch, Marco Prinz
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引用次数: 0

摘要

转录因子 IRF8 在小胶质细胞的出生后早期发育、成年期和疾病期间具有重要功能。
本文章由计算机程序翻译，如有差异，请以英文原文为准。

IRF8 as durable architect of the microglial chromatin landscape

IRF8 as durable architect of the microglial chromatin landscape

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IRF8 as durable architect of the microglial chromatin landscape
The transcription factor IRF8 has an essential function in microglia during early postnatal development, adulthood and disease.
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来源期刊
Nature Immunology
Nature Immunology 医学-免疫学
CiteScore
40.00
自引率
2.30%
发文量
248
审稿时长
4-8 weeks
期刊介绍： Nature Immunology is a monthly journal that publishes the highest quality research in all areas of immunology. The editorial decisions are made by a team of full-time professional editors. The journal prioritizes work that provides translational and/or fundamental insight into the workings of the immune system. It covers a wide range of topics including innate immunity and inflammation, development, immune receptors, signaling and apoptosis, antigen presentation, gene regulation and recombination, cellular and systemic immunity, vaccines, immune tolerance, autoimmunity, tumor immunology, and microbial immunopathology. In addition to publishing significant original research, Nature Immunology also includes comments, News and Views, research highlights, matters arising from readers, and reviews of the literature. The journal serves as a major conduit of top-quality information for the immunology community.
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