反囊膜突起在小鼠早期胚胎中泵送液体。

IF 17.3 1区生物学 Q1 CELL BIOLOGY

Nature Cell Biology Pub Date : 2024-09-20 DOI:10.1038/s41556-024-01510-y

引用次数: 0

摘要

在小鼠的早期发育过程中，充满液体的管腔会使胚胎膨胀。研究发现，在细胞-细胞接触处会形成被称为 "反向出血点 "的膜突起。反向凸起充填和卸载的循环就像液压泵一样，促进了管腔的形成。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Inverse bleb membrane protrusions pump fluid within the early mouse embryo

查看原文本刊更多论文

Inverse bleb membrane protrusions pump fluid within the early mouse embryo

During early mouse development, a fluid-filled lumen inflates the embryo. Membrane protrusions called inverse blebs have been found to form at cell–cell contacts. Cycles of inverse bleb filling and unloading act as hydraulic pumps and contribute to the formation of the lumen.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Nature Cell Biology 生物-细胞生物学

CiteScore

28.40

自引率

0.90%

发文量

219

审稿时长

3 months

期刊介绍： Nature Cell Biology, a prestigious journal, upholds a commitment to publishing papers of the highest quality across all areas of cell biology, with a particular focus on elucidating mechanisms underlying fundamental cell biological processes. The journal's broad scope encompasses various areas of interest, including but not limited to: -Autophagy -Cancer biology -Cell adhesion and migration -Cell cycle and growth -Cell death -Chromatin and epigenetics -Cytoskeletal dynamics -Developmental biology -DNA replication and repair -Mechanisms of human disease -Mechanobiology -Membrane traffic and dynamics -Metabolism -Nuclear organization and dynamics -Organelle biology -Proteolysis and quality control -RNA biology -Signal transduction -Stem cell biology