指南:百科全书 - 新内容?局部晚期直肠癌。

IF 2 4区 医学 Q3 ONCOLOGY
Ralf-Dieter Hofheinz,Dirk Arnold,Markus Borner,Wolfgang Eisterer,Gunnar Folprecht,Michael Ghadimi,Ullrich Graeven,Birgit Grünberger,Holger Hebart,Susanna Hegewisch-Becker,Volker Heinemann,Ron Pritzkuleit,Claus Rödel,Holger Rumpold,Tanja Trarbach,,Bernhard Wörmann
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引用次数: 0

摘要

本文简要总结了最近出版的德国、奥地利和瑞士关于局部晚期直肠癌治疗指南中与临床相关的新内容。主要内容包括:(i) 对具有高风险特征的直肠癌采用全新药辅助治疗 (TNT);(ii) 对局部复发风险较低的患者采用新药辅助化疗;(iii) 对 MSI 高/dMMR 直肠癌患者采用多司马单抗进行免疫治疗;(iv) 将保留器官作为治疗目标。由于存在多种循证治疗方案,因此需要多学科团队进行深入讨论,并向患者提供有关治疗目标、方案和各种治疗方法风险的专门信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Guidelines: onkopedia - what´s new? Locally advanced rectal cancer.
This article briefly summarizes clinically relevant new aspects of the recently published German, Austrian and Swiss onkopedia guideline for the treatment of locally advanced rectal cancer. Main aspects comprise (i) the use of total neoadjuvant therapy (TNT) for rectal cancers with high risk features, (ii) treatment with neoadjuvant chemotherapy for patient with a low risk for local recurrence, (iii) immunotherapy using dostarlimab in patients with MSI high /dMMR rectal cancer as well as (iv) intended organ preservation as a treatment goal. The availability of several evidence-based treatment options requires intensive discussion within the multidisciplinary team as well as dedicated information for patients about treatment goals, options and risks of individual treatment approaches.
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来源期刊
CiteScore
3.20
自引率
0.00%
发文量
84
期刊介绍: With the first issue in 2014, the journal ''Onkologie'' has changed its title to ''Oncology Research and Treatment''. By this change, publisher and editor set the scene for the further development of this interdisciplinary journal. The English title makes it clear that the articles are published in English – a logical step for the journal, which is listed in all relevant international databases. For excellent manuscripts, a ''Fast Track'' was introduced: The review is carried out within 2 weeks; after acceptance the papers are published online within 14 days and immediately released as ''Editor’s Choice'' to provide the authors with maximum visibility of their results. Interesting case reports are published in the section ''Novel Insights from Clinical Practice'' which clearly highlights the scientific advances which the report presents.
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