眶周紫癜可能是原发性轻链淀粉样变性的唯一初始症状：病例报告。

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

World Journal of Clinical Cases Pub Date : 2024-09-16 DOI:10.12998/wjcc.v12.i26.5946

Xiu-Feng Wang,Ting Li,Man Yang,Yan Huang

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引用次数: 0

摘要

背景原发性轻链淀粉样变性是一种罕见的复杂疾病，临床特征复杂，早期极易误诊和漏诊。病例摘要我们报告了一例 47 岁女性患者的病例，该患者最初仅有眶周紫癜症状，未引起足够重视。随着病情的发展，她逐渐出现胸腔积液，经过系统的诊断和治疗，她被确诊为 "原发性轻链淀粉样变性"。结论眶周紫癜可能是原发性轻链淀粉样变性的唯一初始症状，我们应该重视初始临床症状仅为眶周紫癜的病例。

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Periorbital purpura can be the only initial symptom of primary light chain amyloidosis: A case report.

BACKGROUND Primary light chain amyloidosis is a rare and complex disease with complex clinical features and is highly susceptible to misdiagnosis and underdiagnosis in the early stages. CASE SUMMARY We report a case of a 47-year-old female patient whose only initial symptom was periorbital purpura, which was not taken seriously enough. As the disease progressed, pleural effusion gradually appeared, and after systematic diagnosis and treatment, she was diagnosed with "primary light chain amyloidosis". She achieved rapid hematological remission after treatment with a daratumumab + bortezomib + cyclophosphamide + dexamethasone regimen. CONCLUSION Periorbital purpura can be the only initial symptom of primary light chain amyloidosis; we should pay attention to the cases where the initial clinical symptoms are only periorbital purpura.

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来源期刊

World Journal of Clinical Cases Medicine-General Medicine

自引率

0.00%

发文量

3384

期刊介绍： The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.