Call for Papers: Academic and Industrial Collaborations in Drug Discovery

Dear Colleagues, Given the considerable interest generated from our Virtual Special Issues on the topic of enabling chemistry technologies in drug discovery, (1,2) the Editorial Board at ACS Medicinal Chemistry Letters has decided to broaden this approach to include the positive impact of academic and industrial collaborations on the drug discovery process. The suggestions listed below for topics that can be covered represent only the tip of the iceberg. The subject matter may include development of new synthetic methodology/total synthesis in terms of applications to medicinal chemistry and chemical biology, as well as potential challenges at the intersection of total synthesis, biology, and medicine; the development of new synthetic methodology to produce better routes to drug candidates; or building blocks for parallel synthesis work or novel fragments for fragment-based drug discovery purposes. This could include photoredox chemistry or catalyst development, high-throughput experimentation-enabled reaction optimization, or chemistry techniques for DNA-encoded library production and screening. We will also include efforts in chemical proteomics, whether it be targeting identification proteomics or off-target profiling; research to identify and validate new targets using chemical probes, including novel photoaffinity probes; and novel and improved analytical methods (e.g., reduction of analysis time, impact of novel MS-based methods). We are open to other hot topic areas such as antibody–drug candidates, targeted protein degradation/molecular glues, small-molecule RNA regulation, and therapeutic area initiatives such as the prevention and treatment of tropical diseases. This research may be done, for example, through sponsored research collaborations or, alternatively, student internships. We look forward to receiving your submissions! Sincerely, The Editorial Team at ACS Medicinal Chemistry Letters ACS Medicinal Chemistry Letters encourages submissions of Letters, Notes, Technical Notes, Microperspectives, and Viewpoints highlighting the importance of academic and industrial collaborations. Submit your manuscript via ACS Paragon Plus and select “Academic and Industrial Collaborations in Drug Discovery” from the Special Issue dropdown box. Submissions will undergo the normal peer-review process and, and if accepted, will be published on a rolling basis. Once the Virtual Special Issue is complete, all articles will be publicized as a virtual collection, which will provide additional exposure for the work. The submission deadline is May 31, 2025. Please consider the Author Guidelines before submitting a manuscript. We welcome presubmission inquiries, which can be sent to eic@medchemlett.acs.org This article references 2 other publications. This article has not yet been cited by other publications.