针对不同皮层运动区的经颅磁刺激模拟电场比较研究

IF 1.8 3区生物学 Q3 BIOLOGY

Bioelectromagnetics Pub Date : 2024-09-16 DOI:10.1002/bem.22523

Jack Jiaqi Zhang, Bella Bingbing Zhang, Zhongfei Bai, Kenneth N. K. Fong

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引用次数: 0

摘要

这项计算模拟研究调查了经颅磁刺激（TMS）诱导的初级运动皮层（M1）和次级运动区电场（EF）的强度。我们的研究结果表明，相对于 M1 的刺激阈值，TMS 在次级运动区诱导的 EF 反应强度存在很大的个体间差异。值得注意的是，辅助运动区的激活需要高强度的刺激，这可能是因为在该区域观察到的头皮到皮层的距离更大。这些发现强调了利用计算模拟进行个性化规划的重要性，从而优化针对大脑皮层运动系统的神经调控策略。

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A comparative study of simulated electric fields of transcranial magnetic stimulation targeting different cortical motor regions

This computational simulation study investigates the strength of transcranial magnetic stimulation (TMS)-induced electric fields (EF) in primary motor cortex (M1) and secondary motor areas. Our results reveal high interindividual variability in the strength of TMS-induced EF responses in secondary motor areas, relative to the stimulation threshold in M1. Notably, the activation of the supplementary motor area requires high-intensity stimulation, which could be attributed to the greater scalp-to-cortex distance observed over this area. These findings emphasize the importance of individualized planning using computational simulation for optimizing neuromodulation strategies targeting the cortical motor system.

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来源期刊

Bioelectromagnetics 生物-生物物理

CiteScore

4.60

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Bioelectromagnetics is published by Wiley-Liss, Inc., for the Bioelectromagnetics Society and is the official journal of the Bioelectromagnetics Society and the European Bioelectromagnetics Association. It is a peer-reviewed, internationally circulated scientific journal that specializes in reporting original data on biological effects and applications of electromagnetic fields that range in frequency from zero hertz (static fields) to the terahertz undulations and visible light. Both experimental and clinical data are of interest to the journal''s readers as are theoretical papers or reviews that offer novel insights into or criticism of contemporary concepts and theories of field-body interactions. The Bioelectromagnetics Society, which sponsors the journal, also welcomes experimental or clinical papers on the domains of sonic and ultrasonic radiation.