土耳其版 5 项干眼症问卷（T-DEQ-5）：翻译、有效性和可靠性。

IF 4.1 3区医学 Q1 OPHTHALMOLOGY

Contact Lens & Anterior Eye Pub Date : 2024-09-17 DOI:10.1016/j.clae.2024.102309

Semra Akkaya Turhan , Elif Bagatur Vurgun , Ece Yalçındağ , Samet Gülkaş , Canan Şanal Toprak , Ayşe Ebru Toker

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引用次数: 0

摘要

目的评估土耳其语翻译的 5 项干眼症问卷（T-DEQ-5）的可靠性和有效性，并将其与眼表疾病指数（OSDI）问卷、泪液破裂时间（TBUT）、角膜染色和 Schirmer 测试结果进行比较。方法采用国际通用的语言验证程序，包括正译、反译成英语、检查翻译质量和对 10 名受试者进行试点测试。翻译和验证后的问卷对 25 名受试者进行了两次测试（第二次测试在三天内进行），以评估测试内信度。研究共招募了 100 名受试者。他们在填写 OSDI 问卷后接受了眼科检查，包括施尔默试验、TBUT 和眼表染色（OSS）。结果受试者的平均年龄为（45.7 ± 16.2）岁，其中 65% 为女性。总体而言，测试-重复测试的可靠性极佳，类内相关系数为 0.95 (95 % CI 0.90-0.98, p < 0.001)。Cronbach's阿尔法信度系数为0.90，表明T-DEQ-5具有很强的内部一致性。通过 ROC 分析比较 T-DEQ-5 和 OSDI 的结果，发现曲线下面积为 0.95，最佳临界值为 6，灵敏度为 81%，特异度为 91%。根据 OSDI 阳性（≥13）和至少一个阳性体征（TBUT 和/或 OSS）进行诊断，在 6 的临界值下，灵敏度为 95%，特异度为 87%。

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The Turkish version of the 5-item Dry Eye Questionnaire (T-DEQ-5): Translation, validity, and reliability

Purpose

To evaluate the reliability and validity of Turkish translation of the 5-item Dry Eye Questionnaire (T-DEQ-5) and to compare it with the Ocular Surface Disease Index (OSDI) questionnaire, tear break-up time (TBUT), corneal staining, and Schirmer test results.

Methods

The linguistic validation procedures adopted internationally, including forward translations, backward translation into English, examination of the translation quality, and a pilot test on 10 subjects, were employed. The translated and validated questionnaire was applied to 25 subjects two-time points (second time within three days) to evaluate the intra-test reliability. One hundred subjects were recruited for the study. They underwent an ophthalmic examination, including Schirmer tests, TBUT, and ocular surface staining (OSS) after completing OSDI questionnaire. Receiver operating characteristics (ROC) were assessed to determine sensitivity and specificity of the T-DEQ-5.

Results

The mean age of subjects was 45.7 ± 16.2 years, with 65 % being female. Overall, the test–retest reliability was excellent with an intra-class correlation coefficient value of 0.95 (95 % CI 0.90–0.98, p < 0.001). The Cronbach’s alpha reliability coefficient was 0.90, which demonstrated a strong level of internal consistency of the T-DEQ-5. Using ROC analysis to compare the results of the T-DEQ-5 with those of the OSDI, the area under the curve was found 0.95, with an optimal cut-off threshold of 6, resulting in 81 % sensitivity and 91 % specificity. Establishing the diagnosis based on a positive OSDI (≥13) and at least one positive sign (TBUT and/or OSS) yielded a sensitivity of 95 % and a specificity of 87 % at the cut-off threshold of 6.

Conclusion

The Turkish version of the DEQ-5 is a valid and reliable questionnaire and capable of differentiating patients with dry eye.

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来源期刊

Contact Lens & Anterior Eye OPHTHALMOLOGY-

CiteScore

7.60

自引率

18.80%

发文量

198

审稿时长

55 days

期刊介绍： Contact Lens & Anterior Eye is a research-based journal covering all aspects of contact lens theory and practice, including original articles on invention and innovations, as well as the regular features of: Case Reports; Literary Reviews; Editorials; Instrumentation and Techniques and Dates of Professional Meetings.