{"title":"使用苯并咪唑类衍生物检测和处理亚硫酰氯的新方法:展望与建议","authors":"N. Kabaňová, Z. Tokárová","doi":"10.1007/s13762-024-06022-8","DOIUrl":null,"url":null,"abstract":"<p>Benzimidazoles are important heterocyclic compounds that exhibit a wide range of pharmacological and biological properties. Among all, sensitivity to Lewis acids provide a possibility to act as a fluorescent detectors for senzing the cathions, radicals, highly reactive low-molecular species with hazardous effects to environment and human health. Herein, we present the design and synthesis of <i>N</i>-((1<i>H</i>-benzo[<i>d</i>]imidazol-2-yl)methyl)cinnamamide (<i>I</i>) for the detection of readily reactive thionyl chloride (SOCl<sub>2</sub>). Treatment of SOCl<sub>2</sub> with a novel benzimidazole-based compound <i>I</i> is accompanied by immediate color change. Although the process is irreversible the change noticeable by eye is profitable for a simple and rapid protection against the SOCl<sub>2</sub> exposure at amounts harmful for surroundings and body. In the context of environmental issue, the chemical reaction between the detector <i>I</i> and thionyl chloride is beneficial for the safe waste disposal. Thionyl chloride is recaptured in the structure of <i>I</i> throughout the reaction leading to a formation of stable compound <i>II</i>. Incorporation of residual traces of SOCl<sub>2</sub> into the structure of organic-type detector <i>I</i> represents effective route to achieve non-reactive and non-damaging derivatives. Accordingly, the organic non-liquid waste is subsequently stored and disposed in a safe manner.</p>","PeriodicalId":589,"journal":{"name":"International Journal of Environmental Science and Technology","volume":"15 1","pages":""},"PeriodicalIF":3.0000,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Novel approach of thionyl chloride detection and disposal using a benzimidazole-based derivative: perspectives and proposals\",\"authors\":\"N. Kabaňová, Z. Tokárová\",\"doi\":\"10.1007/s13762-024-06022-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Benzimidazoles are important heterocyclic compounds that exhibit a wide range of pharmacological and biological properties. Among all, sensitivity to Lewis acids provide a possibility to act as a fluorescent detectors for senzing the cathions, radicals, highly reactive low-molecular species with hazardous effects to environment and human health. Herein, we present the design and synthesis of <i>N</i>-((1<i>H</i>-benzo[<i>d</i>]imidazol-2-yl)methyl)cinnamamide (<i>I</i>) for the detection of readily reactive thionyl chloride (SOCl<sub>2</sub>). Treatment of SOCl<sub>2</sub> with a novel benzimidazole-based compound <i>I</i> is accompanied by immediate color change. Although the process is irreversible the change noticeable by eye is profitable for a simple and rapid protection against the SOCl<sub>2</sub> exposure at amounts harmful for surroundings and body. In the context of environmental issue, the chemical reaction between the detector <i>I</i> and thionyl chloride is beneficial for the safe waste disposal. Thionyl chloride is recaptured in the structure of <i>I</i> throughout the reaction leading to a formation of stable compound <i>II</i>. Incorporation of residual traces of SOCl<sub>2</sub> into the structure of organic-type detector <i>I</i> represents effective route to achieve non-reactive and non-damaging derivatives. Accordingly, the organic non-liquid waste is subsequently stored and disposed in a safe manner.</p>\",\"PeriodicalId\":589,\"journal\":{\"name\":\"International Journal of Environmental Science and Technology\",\"volume\":\"15 1\",\"pages\":\"\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2024-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Environmental Science and Technology\",\"FirstCategoryId\":\"93\",\"ListUrlMain\":\"https://doi.org/10.1007/s13762-024-06022-8\",\"RegionNum\":4,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Environmental Science and Technology","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1007/s13762-024-06022-8","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 0
摘要
苯并咪唑是重要的杂环化合物,具有广泛的药理和生物学特性。其中,对路易斯酸的敏感性为荧光检测器提供了可能性,可用于检测对环境和人类健康有害的阴离子、自由基、高活性低分子物种。在此,我们介绍了 N-((1H-苯并[d]咪唑-2-基)甲基)肉桂酰胺 (I) 的设计与合成,用于检测易反应的亚硫酰氯 (SOCl2)。用新型苯并咪唑类化合物 I 处理 SOCl2 时,颜色会立即发生变化。虽然这一过程是不可逆的,但肉眼可察觉的变化有利于提供简单快速的保护,避免接触对周围环境和人体有害的 SOCl2。就环境问题而言,检测器 I 和亚硫酰氯之间的化学反应有利于废物的安全处理。在整个反应过程中,亚硫酰氯被重新吸收到 I 的结构中,形成稳定的化合物 II。将残留的微量 SOCl2 加入有机型检测器 I 的结构中,是实现无反应和无损害衍生物的有效途径。因此,有机非液体废物随后可以安全地储存和处理。
Novel approach of thionyl chloride detection and disposal using a benzimidazole-based derivative: perspectives and proposals
Benzimidazoles are important heterocyclic compounds that exhibit a wide range of pharmacological and biological properties. Among all, sensitivity to Lewis acids provide a possibility to act as a fluorescent detectors for senzing the cathions, radicals, highly reactive low-molecular species with hazardous effects to environment and human health. Herein, we present the design and synthesis of N-((1H-benzo[d]imidazol-2-yl)methyl)cinnamamide (I) for the detection of readily reactive thionyl chloride (SOCl2). Treatment of SOCl2 with a novel benzimidazole-based compound I is accompanied by immediate color change. Although the process is irreversible the change noticeable by eye is profitable for a simple and rapid protection against the SOCl2 exposure at amounts harmful for surroundings and body. In the context of environmental issue, the chemical reaction between the detector I and thionyl chloride is beneficial for the safe waste disposal. Thionyl chloride is recaptured in the structure of I throughout the reaction leading to a formation of stable compound II. Incorporation of residual traces of SOCl2 into the structure of organic-type detector I represents effective route to achieve non-reactive and non-damaging derivatives. Accordingly, the organic non-liquid waste is subsequently stored and disposed in a safe manner.
期刊介绍:
International Journal of Environmental Science and Technology (IJEST) is an international scholarly refereed research journal which aims to promote the theory and practice of environmental science and technology, innovation, engineering and management.
A broad outline of the journal''s scope includes: peer reviewed original research articles, case and technical reports, reviews and analyses papers, short communications and notes to the editor, in interdisciplinary information on the practice and status of research in environmental science and technology, both natural and man made.
The main aspects of research areas include, but are not exclusive to; environmental chemistry and biology, environments pollution control and abatement technology, transport and fate of pollutants in the environment, concentrations and dispersion of wastes in air, water, and soil, point and non-point sources pollution, heavy metals and organic compounds in the environment, atmospheric pollutants and trace gases, solid and hazardous waste management; soil biodegradation and bioremediation of contaminated sites; environmental impact assessment, industrial ecology, ecological and human risk assessment; improved energy management and auditing efficiency and environmental standards and criteria.