脱水对年轻健康成年人中心血压的影响

IF 1.3 4区 医学 Q4 PHYSIOLOGY
Madeleine L. Giddings, Jacob P. Auringer, Nathan F. Meier, Elizabeth C. Lefferts, Chong Wang, Lindsay Kane‐Barnese
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引用次数: 0

摘要

目的肱动脉血压 (BP) 是目前血压评估的黄金标准;然而,脉搏波速度 (PWV) 和中心血压 (CBP) 的测量可能会对心血管健康状况的评估做出独特的贡献。到目前为止,CBP 和脉搏波速度的评估标准尚未涉及水合状态对正确测量的影响。为了了解水合的影响,脉搏波速度和 CBP 应在无水和缺水状态下进行测量。方法 43 名年轻、健康的参与者(21 ± 2 岁)完成了一项脱水方案,利用适度的有氧活动直至体重减轻 1%-2%。脱水前和脱水后测量脉搏波速度和CBP。结果未观察到水合状态变化(体重减轻 %)与脉搏波速度(β = 0.05,p = 0.78)或中心舒张压(β = -3.8,p = 0.10)之间有明显关系。总之,在测量 CBP 或脉搏波速度之前评估水合状态对于年轻、健康的人来说可能是不必要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
‘Effects of dehydration on central blood pressure in young healthy adults’
PurposeBrachial blood pressure (BP) is the current gold standard for BP assessment; however, measures of pulse wave velocity (PWV) and central blood pressure (CBP) may contribute uniquely to assessment of cardiovascular health status. As of yet, standards for assessment of CBP and PWV have not addressed the impact of hydration status on proper measurement. To understand the impact of hydration, PWV and CBP should be measured in a euhydrated and hypohydrated state.MethodsForty‐three young, healthy participants (21 ± 2 years) completed a dehydration protocol utilizing moderate aerobic activity until they lost 1%–2% of their body weight. PWV and CBP were measured before and following the dehydration protocol. Linear regression was utilized to assess change in hydration status and change in PWV and CBP.ResultsNo significant relationships were observed between the change in hydration status (% body weight lost) and PWV (β = 0.05, p = 0.78) or central diastolic BP (β = −3.8, p = 0.10), however, a significant relationship was observed with central systolic BP (β = −5.0, p = 0.03).DiscussionIn conclusion, the assessment of hydration status before measurement of CBP or PWV may not be necessary in young, healthy individuals.
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来源期刊
CiteScore
3.40
自引率
5.60%
发文量
62
审稿时长
6-12 weeks
期刊介绍: Clinical Physiology and Functional Imaging publishes reports on clinical and experimental research pertinent to human physiology in health and disease. The scope of the Journal is very broad, covering all aspects of the regulatory system in the cardiovascular, renal and pulmonary systems with special emphasis on methodological aspects. The focus for the journal is, however, work that has potential clinical relevance. The Journal also features review articles on recent front-line research within these fields of interest. Covered by the major abstracting services including Current Contents and Science Citation Index, Clinical Physiology and Functional Imaging plays an important role in providing effective and productive communication among clinical physiologists world-wide.
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