光动力疗法治疗一名患有系统性红斑狼疮的年轻女性尖锐湿疣和 I 级宫颈上皮内瘤变：病例报告

IF 1.9 4区医学 Q3 DERMATOLOGY

Clinical, Cosmetic and Investigational Dermatology Pub Date : 2024-09-14 DOI:10.2147/ccid.s479720

Na Zhang, Hongping Ge, Xinru Chen, Tianhui Ye, Weikang Shi, Meiyan Wang

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引用次数: 0

摘要

摘要：尖锐湿疣（CA）俗称生殖器疣，是一种流行的性传播疾病，主要由低危型人类乳头瘤病毒（HPV）6型和11型引起。本病例报告概述了在一名接受免疫抑制治疗的系统性红斑狼疮（SLE）年轻女性患者身上成功使用光动力疗法（PDT）治疗大面积尖锐湿疣的过程。该患者还患有宫颈上皮内瘤变Ⅰ级。首先使用二氧化碳激光治疗去除一些表面疣体，然后进行光动力疗法，结果令人满意。经过七次治疗后，疣体被成功去除。风湿免疫科、妇科和皮肤科的跨学科合作为综合治疗提供了便利。本病例强调了光动力疗法治疗尖锐湿疣的有效性和安全性，并提示了其作为年轻系统性红斑狼疮患者类似病症的替代治疗方法的潜力。关键词：尖锐湿疣；光动力疗法；系统性红斑狼疮

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Photodynamic Therapy for Condyloma Acuminatum and Cervical Intraepithelial Neoplasia Grade I in a Young Female Patient with Systemic Lupus Erythematosus: A Case Report

Abstract: Condyloma acuminatum (CA), commonly known as anogenital warts, is a prevalent sexually transmitted disease primarily caused by low risk human papillomavirus (HPV) types 6 and 11. This case report outlines the successful use of photodynamic therapy (PDT) to treat extensive condyloma acuminatum in a young female patient with systemic lupus erythematosus (SLE) undergoing immunosuppressive treatment. The patient also had cervical intraepithelial neoplasia grade I. Carbon dioxide laser treatment were initially used to remove some surface warts, followed by PDT, resulting in satisfactory outcomes. After seven sessions, the warty growths were successfully removed. Interdisciplinary collaboration, involving rheumatology, gynecology, and dermatology, facilitated comprehensive management. This case highlights the efficacy and safety of PDT in treating condyloma acuminatum and suggests its potential as an alternative treatment for young SLE patients with similar conditions.

Keywords: condyloma acuminatum, photodynamic therapy, systemic lupus erythematosus

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来源期刊

Clinical, Cosmetic and Investigational Dermatology Medicine-Dermatology

CiteScore

2.80

自引率

4.30%

发文量

353

审稿时长

16 weeks

期刊介绍： Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.