OAGB 和 SADJB-SG 的安全性和有效性比较研究：一项回顾性研究

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2024-09-19 DOI:10.2147/dmso.s484616

Mingyue Shang, Zhehong Li, Dexiao Du, Guangzhong Xu, Dongbo Lian, Zhaohui Liao, Dezhong Wang, Buhe Amin, Zheng Wang, Weijian Chen, Nengwei Zhang, Liang Wang

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引用次数: 0

摘要

目的：单吻合胃旁路术（OAGB）和单吻合十二指肠空肠旁路术与袖状胃切除术（SADJB-SG）都是从传统胃旁路术改良而来，可治疗肥胖症及相关并发症。然而，目前还没有关于这两种手术的安全性和有效性的比较研究：我们对 2019 年 6 月至 2021 年 6 月期间在本院接受 OAGB 和 SADJB-SG 手术的患者的术前基线数据进行了回顾性分析。我们收集了两年内的术后数据，包括体重变化、2 型糖尿病（T2DM）改善情况和并发症发生率。随后对两种手术方法的安全性和有效性进行了综合评估：结果：共有 63 名患者完成了这项研究的随访。随访24个月时，OAGB和SADJB-SG的超重率（EWL%）分别为73.970± 5.005和75.652± 7.953（P值=0.310）；总减重率（TWL%）分别为24.006± 8.231和23.171± 6.600（P值=0.665）。两组的糖尿病缓解率分别为 71.429% 和 69.048%（P 值 = 0.846）。OAGB的费用为（55088.208±1508.220）元，明显低于SADJB-SG的（57538.195±1374.994）元（P值< 0.001）：两种手术方法在安全性和有效性方面都是可靠的，且各有优势。关键词：单吻合口胃旁路术；单吻合口十二指肠空肠旁路术联合袖状胃切除术；安全性；疗效

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Comparative Study for Safety and Efficacy of OAGB and SADJB-SG: A Retrospective Study

Purpose: Obesity and related complications are managed by One Anastomosis Gastric Bypass (OAGB) and Single Anastomosis Duodeno-Jejunal Bypass with Sleeve Gastrectomy (SADJB-SG), both of which are adapted from traditional gastric bypass procedures. However, there are no current comparative studies on the safety and efficacy of these two surgical procedures.
Patients and Methods: Preoperative baseline data of patients who had undergone OAGB and SADJB-SG surgeries from June 2019 to June 2021 were retrospectively analyzed at our bariatric facility. Postoperative data, including weight changes, improvement in type 2 diabetes (T2DM), and complication rates were collected over 2 years. This was followed by a comprehensive evaluation of the safety and efficacy of the two surgical procedures.
Results: A total of 63 patients completed the follow-up in this study. At the 24-month follow-up, excess weight loss percentage (EWL%) for the OAGB and SADJB-SG was 73.970± 5.005 and 75.652± 7.953, respectively (P-value = 0.310); total weight loss percentage (TWL%) was 24.006± 8.231 and 23.171± 6.600, respectively (P-value = 0.665). The diabetes remission rates for the two groups were 71.429% and 69.048%, respectively (P-value = 0.846). The cost for OAGB was 55088.208± 1508.220 yuan, which was significantly lower than the 57538.195± 1374.994 yuan for SADJB-SG (P-value< 0.001).
Conclusion: The two surgical procedures are reliable in terms of safety and efficacy, and each has distinct advantages. While OAGB has reduced operational expenses, SADJB-SG offers a broader range of applicability.

Keywords: one anastomosis gastric bypass, single anastomosis duodeno-jejunal bypass with sleeve gastrectomy, safety, efficacy

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464