三种不同心脏瓣膜在三种不同血流动力学条件下的血流动力学性能、三维流场和湍流水平比较

IF 3 2区 医学 Q3 ENGINEERING, BIOMEDICAL
Lorenzo Ferrari, Dominik Obrist
{"title":"三种不同心脏瓣膜在三种不同血流动力学条件下的血流动力学性能、三维流场和湍流水平比较","authors":"Lorenzo Ferrari, Dominik Obrist","doi":"10.1007/s10439-024-03584-z","DOIUrl":null,"url":null,"abstract":"<p>The hemodynamic performance of different prosthetic heart valves is difficult to compare among studies due to a variety of test conditions and experimental techniques. Existing studies are typically limited to one family of valves (biological or mechanical) and testing conditions of 5l/min and often lack sufficient spatial resolution. To address these limitations, a pulse duplicator with a multi-view imaging system (Tomo-PIV) was employed to investigate the three-dimensional flow field in the aortic root of three different valves: a tri-leaflet mechanical heart valve (TRIFLO, Novostia), a bi-leaflet mechanical heart valve (On-X, Artivion), and a biological heart valve (Perimount, Edwards Lifesciences). The valves were tested at low (3 l/min), normal (5 l/min), and elevated (7 l/min) cardiac output <span>\\((CO)\\)</span> under hypotensive (40/60mmHg), normotensive (80/120mmHg), and moderate hypertensive (105/170mmHg) pressure conditions, respectively. Compared to the Perimount, peak mean velocity was − 33%, − 24%, − 18% for the TRIFLO and − 32%, − 20%, − 11% for the On-X at low, moderate, and elevated <span>\\(CO\\)</span>, respectively. Corresponding peak <span>\\(TKE\\)</span> values decreased by − 66%, − 57%, − 44% (TRIFLO) and − 60%, − 50%, − 36% (On-X). At low <span>\\(CO\\)</span>, <span>\\(EOA\\)</span> was lower for Perimount (1.07cm<sup>2</sup>) than for TRIFLO (1.47cm<sup>2</sup>) and On-X (1.52cm<sup>2</sup>), while it increased for elevated <span>\\(CO\\)</span> to 2.75cm<sup>2</sup> (TRIFLO) and 2.16cm<sup>2</sup> (Perimount and On-X). For all valves, increasing <span>\\(CO\\)</span> led to increased flow velocities, higher <span>\\(EOA,\\)</span> and higher levels of turbulence, and the spatial influence of the valve on the flow field in the ascending aorta was extended. <span>\\(TKE\\)</span> peaked closer to the STJ than for TRIFLO and Perimount.</p>","PeriodicalId":7986,"journal":{"name":"Annals of Biomedical Engineering","volume":null,"pages":null},"PeriodicalIF":3.0000,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of Hemodynamic Performance, Three-Dimensional Flow Fields, and Turbulence Levels for Three Different Heart Valves at Three Different Hemodynamic Conditions\",\"authors\":\"Lorenzo Ferrari, Dominik Obrist\",\"doi\":\"10.1007/s10439-024-03584-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The hemodynamic performance of different prosthetic heart valves is difficult to compare among studies due to a variety of test conditions and experimental techniques. Existing studies are typically limited to one family of valves (biological or mechanical) and testing conditions of 5l/min and often lack sufficient spatial resolution. To address these limitations, a pulse duplicator with a multi-view imaging system (Tomo-PIV) was employed to investigate the three-dimensional flow field in the aortic root of three different valves: a tri-leaflet mechanical heart valve (TRIFLO, Novostia), a bi-leaflet mechanical heart valve (On-X, Artivion), and a biological heart valve (Perimount, Edwards Lifesciences). The valves were tested at low (3 l/min), normal (5 l/min), and elevated (7 l/min) cardiac output <span>\\\\((CO)\\\\)</span> under hypotensive (40/60mmHg), normotensive (80/120mmHg), and moderate hypertensive (105/170mmHg) pressure conditions, respectively. Compared to the Perimount, peak mean velocity was − 33%, − 24%, − 18% for the TRIFLO and − 32%, − 20%, − 11% for the On-X at low, moderate, and elevated <span>\\\\(CO\\\\)</span>, respectively. Corresponding peak <span>\\\\(TKE\\\\)</span> values decreased by − 66%, − 57%, − 44% (TRIFLO) and − 60%, − 50%, − 36% (On-X). At low <span>\\\\(CO\\\\)</span>, <span>\\\\(EOA\\\\)</span> was lower for Perimount (1.07cm<sup>2</sup>) than for TRIFLO (1.47cm<sup>2</sup>) and On-X (1.52cm<sup>2</sup>), while it increased for elevated <span>\\\\(CO\\\\)</span> to 2.75cm<sup>2</sup> (TRIFLO) and 2.16cm<sup>2</sup> (Perimount and On-X). For all valves, increasing <span>\\\\(CO\\\\)</span> led to increased flow velocities, higher <span>\\\\(EOA,\\\\)</span> and higher levels of turbulence, and the spatial influence of the valve on the flow field in the ascending aorta was extended. <span>\\\\(TKE\\\\)</span> peaked closer to the STJ than for TRIFLO and Perimount.</p>\",\"PeriodicalId\":7986,\"journal\":{\"name\":\"Annals of Biomedical Engineering\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2024-09-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Biomedical Engineering\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1007/s10439-024-03584-z\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Biomedical Engineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1007/s10439-024-03584-z","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0

摘要

由于测试条件和实验技术的不同,不同人工心脏瓣膜的血液动力学性能很难在不同研究中进行比较。现有的研究通常仅限于一种瓣膜(生物或机械瓣膜)和 5 升/分钟的测试条件,而且往往缺乏足够的空间分辨率。为了解决这些局限性,我们采用了带有多视角成像系统(Tomo-PIV)的脉冲复制器来研究三种不同瓣膜主动脉根部的三维流场:三叶机械心脏瓣膜(TRIFLO,Novostia)、双叶机械心脏瓣膜(On-X,Artivion)和生物心脏瓣膜(Perimount,Edwards Lifesciences)。这些瓣膜分别在低血压(40/60mmHg)、正常血压(80/120mmHg)和中度高血压(105/170mmHg)压力条件下进行低(3 升/分钟)、正常(5 升/分钟)和高(7 升/分钟)心输出量((CO))测试。与 Perimount 相比,TRIFLO 的峰值平均速度在低、中、高 \(CO\ )时分别为 - 33%、 - 24%、 - 18%,On-X 为 - 32%、 - 20%、 - 11%。相应的峰值 \(TKE)值分别下降了 - 66%、- 57%、- 44%(TRIFLO)和 - 60%、- 50%、- 36%(On-X)。在低\(CO)时,Perimount(1.07cm2)的\(EOA)低于 TRIFLO(1.47cm2)和 On-X(1.52cm2),而在\(CO)升高时,\(EOA)增加到 2.75cm2(TRIFLO)和 2.16cm2(Perimount 和 On-X)。对于所有瓣膜,\(CO\)的增加导致流速增加、\(EOA,\)增加和湍流水平增加,瓣膜对升主动脉流场的空间影响扩大。\与 TRIFLO 和 Perimount 相比,TKE 的峰值更靠近 STJ。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Comparison of Hemodynamic Performance, Three-Dimensional Flow Fields, and Turbulence Levels for Three Different Heart Valves at Three Different Hemodynamic Conditions

Comparison of Hemodynamic Performance, Three-Dimensional Flow Fields, and Turbulence Levels for Three Different Heart Valves at Three Different Hemodynamic Conditions

The hemodynamic performance of different prosthetic heart valves is difficult to compare among studies due to a variety of test conditions and experimental techniques. Existing studies are typically limited to one family of valves (biological or mechanical) and testing conditions of 5l/min and often lack sufficient spatial resolution. To address these limitations, a pulse duplicator with a multi-view imaging system (Tomo-PIV) was employed to investigate the three-dimensional flow field in the aortic root of three different valves: a tri-leaflet mechanical heart valve (TRIFLO, Novostia), a bi-leaflet mechanical heart valve (On-X, Artivion), and a biological heart valve (Perimount, Edwards Lifesciences). The valves were tested at low (3 l/min), normal (5 l/min), and elevated (7 l/min) cardiac output \((CO)\) under hypotensive (40/60mmHg), normotensive (80/120mmHg), and moderate hypertensive (105/170mmHg) pressure conditions, respectively. Compared to the Perimount, peak mean velocity was − 33%, − 24%, − 18% for the TRIFLO and − 32%, − 20%, − 11% for the On-X at low, moderate, and elevated \(CO\), respectively. Corresponding peak \(TKE\) values decreased by − 66%, − 57%, − 44% (TRIFLO) and − 60%, − 50%, − 36% (On-X). At low \(CO\), \(EOA\) was lower for Perimount (1.07cm2) than for TRIFLO (1.47cm2) and On-X (1.52cm2), while it increased for elevated \(CO\) to 2.75cm2 (TRIFLO) and 2.16cm2 (Perimount and On-X). For all valves, increasing \(CO\) led to increased flow velocities, higher \(EOA,\) and higher levels of turbulence, and the spatial influence of the valve on the flow field in the ascending aorta was extended. \(TKE\) peaked closer to the STJ than for TRIFLO and Perimount.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Annals of Biomedical Engineering
Annals of Biomedical Engineering 工程技术-工程:生物医学
CiteScore
7.50
自引率
15.80%
发文量
212
审稿时长
3 months
期刊介绍: Annals of Biomedical Engineering is an official journal of the Biomedical Engineering Society, publishing original articles in the major fields of bioengineering and biomedical engineering. The Annals is an interdisciplinary and international journal with the aim to highlight integrated approaches to the solutions of biological and biomedical problems.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信