雄激素遗传学小鼠模型的相关性、策略和附加值

IF 3.2 2区医学 Q1 ANDROLOGY

Andrology Pub Date : 2024-09-19 DOI:10.1111/andr.13761

Vertika Singh, John C. Schimenti

引用次数: 0

摘要

男性不育症在全世界都很普遍，其中相当一部分病例被认为与遗传有关。对致病基因的研究仅限于实验，因此人们广泛使用小鼠来确定生育所需的基因并了解其功能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Relevance, strategies, and added value of mouse models in androgenetics

Male Infertility is a prevalent condition worldwide, and a substantial fraction of cases are thought to have a genetic basis. Investigations into the responsible genes is limited experimentally, so mice have been used extensively to identify genes required for fertility and to understand their functions.

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来源期刊

Andrology ANDROLOGY-

CiteScore

9.10

自引率

6.70%

发文量

200

期刊介绍： Andrology is the study of the male reproductive system and other male gender related health issues. Andrology deals with basic and clinical aspects of the male reproductive system (gonads, endocrine and accessory organs) in all species, including the diagnosis and treatment of medical problems associated with sexual development, infertility, sexual dysfunction, sex hormone action and other urological problems. In medicine, Andrology as a specialty is a recent development, as it had previously been considered a subspecialty of urology or endocrinology