Yihan Zhang, Yansi Lyu, Tingyin Lin, Luotai Chen, Zhuolin Liu, Yanting Ou, Xiangwen Xu, Mengfan Wu, Lin Luo, Jun Feng, Dandan Liu
{"title":"注射透明质酸后由大肠沙雷氏菌引起的晚期皮下感染:病例报告和系统回顾","authors":"Yihan Zhang, Yansi Lyu, Tingyin Lin, Luotai Chen, Zhuolin Liu, Yanting Ou, Xiangwen Xu, Mengfan Wu, Lin Luo, Jun Feng, Dandan Liu","doi":"10.1111/jocd.16571","DOIUrl":null,"url":null,"abstract":"BackgroundThe field of cosmetic filler injection has experienced rapid development over the past two decades, especially in facial augmentation utilizing hyaluronic acid (HA) fillers. Gram‐negative bacteria are found to be the main pathogens of infective nodules after HA injection. The occurrence of cutaneous infections attributed to <jats:italic>Serratia marcescens</jats:italic> is exceedingly rare and predominantly noted in patients with compromised immune systems.AimsTo summarize the clinical features, diagnosis, and treatment of subcutaneous infection caused by <jats:italic>Serratia marcescens</jats:italic> following hyaluronic acid injection.Patients/MethodsA rare case of cutaneous <jats:italic>Serratia marcescens</jats:italic> infection following hyaluronic acid injection was presented. A comprehensive review of the published literature describing the management of skin infection caused by <jats:italic>S. marcescens</jats:italic> in immunocompetent patients was then conducted, which encompassed three case series and eight case reports published between 1999 and 2017. Data extraction included information on authors, gender, age, signs and symptoms, previous treatment, corresponding management strategies, and follow‐up duration.Results<jats:italic>Serratia marcescens</jats:italic> were isolated in abscesses (<jats:italic>n</jats:italic> = 6, 35.29%), painful nodules (<jats:italic>n</jats:italic> = 2, 11.76%), ulcers (<jats:italic>n</jats:italic> = 6, 35.29%), and others (<jats:italic>n</jats:italic> = 3, 17.65%). In cases providing salvage plans (<jats:italic>n</jats:italic> = 11), quinolones were shown to be the most effective antibiotics for salvage, with eight full recoveries (72.73%), and trimethoprim‐sulfamethoxazole was the second most useful antibiotic (18.18%).ConclusionsWith the help of pathogen examination and drug‐sensitive tests, sensitive aminoglycosides, quinolone (especially moxifloxacin), or TMP‐SMX for at least 2 weeks can be considered as the first‐line treatment of late subcutaneous infection caused by <jats:italic>Serratia marcescens</jats:italic> following hyaluronic acid injection.","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Late Subcutaneous Infection Caused by Serratia marcescens Following Hyaluronic Acid Injection: A Case Report and Systemic Review\",\"authors\":\"Yihan Zhang, Yansi Lyu, Tingyin Lin, Luotai Chen, Zhuolin Liu, Yanting Ou, Xiangwen Xu, Mengfan Wu, Lin Luo, Jun Feng, Dandan Liu\",\"doi\":\"10.1111/jocd.16571\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"BackgroundThe field of cosmetic filler injection has experienced rapid development over the past two decades, especially in facial augmentation utilizing hyaluronic acid (HA) fillers. Gram‐negative bacteria are found to be the main pathogens of infective nodules after HA injection. The occurrence of cutaneous infections attributed to <jats:italic>Serratia marcescens</jats:italic> is exceedingly rare and predominantly noted in patients with compromised immune systems.AimsTo summarize the clinical features, diagnosis, and treatment of subcutaneous infection caused by <jats:italic>Serratia marcescens</jats:italic> following hyaluronic acid injection.Patients/MethodsA rare case of cutaneous <jats:italic>Serratia marcescens</jats:italic> infection following hyaluronic acid injection was presented. A comprehensive review of the published literature describing the management of skin infection caused by <jats:italic>S. marcescens</jats:italic> in immunocompetent patients was then conducted, which encompassed three case series and eight case reports published between 1999 and 2017. Data extraction included information on authors, gender, age, signs and symptoms, previous treatment, corresponding management strategies, and follow‐up duration.Results<jats:italic>Serratia marcescens</jats:italic> were isolated in abscesses (<jats:italic>n</jats:italic> = 6, 35.29%), painful nodules (<jats:italic>n</jats:italic> = 2, 11.76%), ulcers (<jats:italic>n</jats:italic> = 6, 35.29%), and others (<jats:italic>n</jats:italic> = 3, 17.65%). In cases providing salvage plans (<jats:italic>n</jats:italic> = 11), quinolones were shown to be the most effective antibiotics for salvage, with eight full recoveries (72.73%), and trimethoprim‐sulfamethoxazole was the second most useful antibiotic (18.18%).ConclusionsWith the help of pathogen examination and drug‐sensitive tests, sensitive aminoglycosides, quinolone (especially moxifloxacin), or TMP‐SMX for at least 2 weeks can be considered as the first‐line treatment of late subcutaneous infection caused by <jats:italic>Serratia marcescens</jats:italic> following hyaluronic acid injection.\",\"PeriodicalId\":15546,\"journal\":{\"name\":\"Journal of Cosmetic Dermatology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-09-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cosmetic Dermatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/jocd.16571\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cosmetic Dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/jocd.16571","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Late Subcutaneous Infection Caused by Serratia marcescens Following Hyaluronic Acid Injection: A Case Report and Systemic Review
BackgroundThe field of cosmetic filler injection has experienced rapid development over the past two decades, especially in facial augmentation utilizing hyaluronic acid (HA) fillers. Gram‐negative bacteria are found to be the main pathogens of infective nodules after HA injection. The occurrence of cutaneous infections attributed to Serratia marcescens is exceedingly rare and predominantly noted in patients with compromised immune systems.AimsTo summarize the clinical features, diagnosis, and treatment of subcutaneous infection caused by Serratia marcescens following hyaluronic acid injection.Patients/MethodsA rare case of cutaneous Serratia marcescens infection following hyaluronic acid injection was presented. A comprehensive review of the published literature describing the management of skin infection caused by S. marcescens in immunocompetent patients was then conducted, which encompassed three case series and eight case reports published between 1999 and 2017. Data extraction included information on authors, gender, age, signs and symptoms, previous treatment, corresponding management strategies, and follow‐up duration.ResultsSerratia marcescens were isolated in abscesses (n = 6, 35.29%), painful nodules (n = 2, 11.76%), ulcers (n = 6, 35.29%), and others (n = 3, 17.65%). In cases providing salvage plans (n = 11), quinolones were shown to be the most effective antibiotics for salvage, with eight full recoveries (72.73%), and trimethoprim‐sulfamethoxazole was the second most useful antibiotic (18.18%).ConclusionsWith the help of pathogen examination and drug‐sensitive tests, sensitive aminoglycosides, quinolone (especially moxifloxacin), or TMP‐SMX for at least 2 weeks can be considered as the first‐line treatment of late subcutaneous infection caused by Serratia marcescens following hyaluronic acid injection.
期刊介绍:
The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques.
The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.