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IF 4.9 2区医学 Q1 CLINICAL NEUROLOGY

Journal of affective disorders Pub Date : 2024-09-14 DOI:10.1016/j.jad.2024.09.079

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引用次数: 0

摘要

方法这项随机对照试验（临床试验编号：NCT06201702）是在土耳其西部地区的一个城市进行的，通过社交媒体公告向患有经前综合症的妇女进行宣传。数据收集时间为 2024 年 1 月 2 日至 2024 年 5 月 15 日。该研究有 60 名参与者（干预组：30 人，对照组：30 人），干预组在两个周期内补充石榴提取物，而对照组不接受任何干预。研究数据通过描述性信息、经前期综合征量表和世界卫生组织生活质量量表收集。数据分析采用 IBM SPSS 23 版软件。采用了卡方检验、配对样本 t 检验和独立样本 t 检验。结果当比较干预组和对照组的经前综合征评分时，发现两组的差异有统计学意义，并观察到干预组的症状在干预后明显减轻（p <.05）。然而，对照组在统计学上未观察到明显变化（p >.05）。在对干预后的生活质量评分进行评估时，发现干预组的社会生活质量高于对照组（p <.05）。结论这项研究表明，石榴可能是一种潜在的天然解决方案，尤其是在减轻经前综合征症状方面，而且还能有效改善社会生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The effect of pomegranate supplementation on symptom severity and quality of life in women with premenstrual syndrome: A randomised controlled trial

Background

The aim of this study was to find out how well pomegranate use affects quality of life and PMS symptoms.

Methods

This randomised controlled trial (Clinical trial number: NCT06201702) was conducted in a city in the western region of Turkey, reaching women with PMS through social media announcements. Data were collected between 2 January 2024 and 15 May 2024. In the study of 60 participants (intervention group: 30, control group: 30), the intervention group was given pomegranate exrat supplementation for 2 cycles, while the control group did not receive any intervention. The research data were collected through a descriptive information, Premenstrual Syndrome Scale and World Health Organisation Quality of Life Scale. IBM SPSS Version 23 software was used for data analysis. Chi-square test, paired sample t-test and independent sample t-test were used. P-value <.05 was considered statistically significant.

Results

When the intervention and control groups were compared in terms of premenstrual syndrome scores, a statistically significant difference was found and it was observed that symptoms decreased significantly in the intervention group after the intervention (p < .05). However, no statistically significant change was observed in the control group (p > .05). When the quality of life scores after the intervention were evaluated, it was seen that the social quality of life of the intervention group was higher than the control group (p < .05).

Conclusions

This study shows that pomegranate may be a potential natural solution, especially in reducing PMS symptoms, and may also be effective in improving social quality of life.

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来源期刊

Journal of affective disorders 医学-精神病学

CiteScore

10.90

自引率

6.10%

发文量

1319

审稿时长

9.3 weeks

期刊介绍： The Journal of Affective Disorders publishes papers concerned with affective disorders in the widest sense: depression, mania, mood spectrum, emotions and personality, anxiety and stress. It is interdisciplinary and aims to bring together different approaches for a diverse readership. Top quality papers will be accepted dealing with any aspect of affective disorders, including neuroimaging, cognitive neurosciences, genetics, molecular biology, experimental and clinical neurosciences, pharmacology, neuroimmunoendocrinology, intervention and treatment trials.