Bing He, Ruiming Wu, Neel Sangani, Pradeep Varathan Pugalenthi, Alice Patania, Shannon L. Risacher, Kwangsik Nho, Liana G. Apostolova, Li Shen, Andrew J. Saykin, Jingwen Yan
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Integrating amyloid imaging and genetics for early risk stratification of Alzheimer's disease
Alzheimer's disease (AD) initiates years prior to symptoms, underscoring the importance of early detection. While amyloid accumulation starts early, individuals with substantial amyloid burden may remain cognitively normal, implying that amyloid alone is not sufficient for early risk assessment.
期刊介绍:
Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.