2020-2022 年 COVID-19 大流行期间丹麦、芬兰、挪威和瑞典的特定病因超额死亡率:利用全国人口数据进行的研究

IF 7.7 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Anton Nilsson, Louise Emilsson, Kasper P. Kepp, Ann Kristin Skrindo Knudsen, Ingeborg Forthun, Christian Madsen, Jonas Björk, Tea Lallukka
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引用次数: 0

摘要

虽然有大量证据表明 COVID-19 大流行的前两年死亡率过高,但没有任何研究对 2020-2022 年整个期间多个国家的超额死亡率进行了特定原因分析。我们研究了丹麦、芬兰、挪威和瑞典在 2020-2022 年期间特定原因导致的超额死亡率,这四个国家的人口构成和福利规定相似,但实施了不同的大流行应对政策。为此,我们利用全国范围内按年龄和性别分层的年度特定病因死亡登记信息,并根据 2010-2019 年的参照期应用线性回归模型预测 2020-2022 年的死亡率。通过对比实际死亡人数和预期死亡人数,得出超额死亡人数。其他分析还采用了普通人群标准化以及人群调整的方法,以考虑到以往的死亡情况。我们的结果显示,除了 COVID-19 导致的死亡(2020-2022 年期间共计 32,491 例)外,所有国家都出现了心血管疾病导致的超额死亡(共计 11,610 例超额死亡),以及 COVID-19 以外的呼吸系统疾病(共计 9878 例)和痴呆症(共计 8721 例)导致的死亡不足。2022 年,心血管疾病导致的超额死亡率在芬兰和挪威尤为明显,2021-2022 年,痴呆症导致的死亡率不足在瑞典尤为明显。总之,虽然 COVID-19 死亡是大流行最明显的后果,但我们的研究结果表明,死亡率还受到不同死因之间和不同时期的替代影响,以及 COVID-19 感染和大流行应对措施的间接后果--尽管在不同国家的影响程度不同。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Cause-specific excess mortality in Denmark, Finland, Norway, and Sweden during the COVID-19 pandemic 2020–2022: a study using nationwide population data

Cause-specific excess mortality in Denmark, Finland, Norway, and Sweden during the COVID-19 pandemic 2020–2022: a study using nationwide population data

While there is substantial evidence on excess mortality in the first two years of the COVID-19 pandemic, no study has conducted a cause-specific analysis of excess mortality for the whole period 2020–2022 across multiple countries. We examined cause-specific excess mortality during 2020–2022 in Denmark, Finland, Norway, and Sweden—four countries with similar demographics and welfare provisions, which implemented different pandemic response policies. To this end, we utilized nationwide register-based information on annual cause-specific deaths stratified by age and sex, and applied linear regression models to predict mortality in 2020–2022 based on the reference period 2010–2019. Excess deaths were obtained by contrasting actual and expected deaths. Additional analyses employed standardization to a common population, as well as population adjustments to account for previous deaths. Our results showed that, besides deaths due to COVID-19 (a total of 32,491 during 2020–2022), all countries experienced excess deaths due to cardiovascular diseases (in total 11,610 excess deaths), and under-mortality due to respiratory diseases other than COVID-19 (in total 9878) and dementia (in total 8721). The excess mortality due to cardiovascular diseases was particularly pronounced in Finland and Norway in 2022, and the under-mortality due to dementia was particularly pronounced in Sweden in 2021–2022. In conclusion, while COVID-19 deaths emerge as the most apparent consequence of the pandemic, our findings suggest that mortality has also been influenced by substitutions between different causes of death and over time, as well as indirect consequences of COVID-19 infection and pandemic responses—albeit to different extents in the different countries.

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来源期刊
European Journal of Epidemiology
European Journal of Epidemiology 医学-公共卫生、环境卫生与职业卫生
CiteScore
21.40
自引率
1.50%
发文量
109
审稿时长
6-12 weeks
期刊介绍: The European Journal of Epidemiology, established in 1985, is a peer-reviewed publication that provides a platform for discussions on epidemiology in its broadest sense. It covers various aspects of epidemiologic research and statistical methods. The journal facilitates communication between researchers, educators, and practitioners in epidemiology, including those in clinical and community medicine. Contributions from diverse fields such as public health, preventive medicine, clinical medicine, health economics, and computational biology and data science, in relation to health and disease, are encouraged. While accepting submissions from all over the world, the journal particularly emphasizes European topics relevant to epidemiology. The published articles consist of empirical research findings, developments in methodology, and opinion pieces.
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