Brigitte A.K. Kriebisch, Christine M.E. Kriebisch, Hamish W.A. Swanson, Daniel Bublitz, Massimo Kube, Alexander M. Bergmann, Alexander van Teijlingen, Zoe MacPherson, Aras Kartouzian, Hendrik Dietz, Matthias Rief, Tell Tuttle, Job Boekhoven
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引用次数: 0
摘要
推动纳米技术领域的发展需要能将化学势转化为工作的新机制,而以 ATP 为燃料的古鞭毛虫旋转电机就是最终的灵感来源。我们描述了由小肽组装而成的微米长的丝带,它能催化纳米级分子燃料的转化。这种转换促使扁平纳米带形态转变为螺旋纳米带,并最终转变为管状纳米带,从而使纳米带旋转起来。值得注意的是,旋转速度和方向性可以通过分子设计进行调整。此外,纳米带还能对周围环境施加 pN 力,从而推动微米大小的物体甚至爬行。我们的工作展示了一种新机制,即利用纳米级化学能为微米级机械提供动力。我们设想,这种新机制将为微型和纳米级自主机械打开大门。
Synthetic flagella spin and contract at the expense of chemical fuel
New mechanisms that transduce chemical potential into work are needed to advance the field of nanotechnology, with the ATP-fueled archaeal flagellar rotational motor being the ultimate inspiration. We describe microns-long ribbons assembled from small peptides that catalyze the conversion of a nanometer-sized molecular fuel. This conversion drives a morphological transition of the flat nanoribbons into helical ones and eventually into tubes, which makes the ribbons spin. Remarkably, the spinning speed and directionality can be tuned by molecular design. Moreover, the nanoribbons exert pN forces on their surroundings, allowing them to push micron-sized objects or even crawl. Our work demonstrates a new mechanism by which chemical energy at the nanometer level is used to power micron-sized machinery. We envision such new mechanisms opening the door to micro- and nanoscale autonomous machines.
期刊介绍:
Chem, affiliated with Cell as its sister journal, serves as a platform for groundbreaking research and illustrates how fundamental inquiries in chemistry and its related fields can contribute to addressing future global challenges. It was established in 2016, and is currently edited by Robert Eagling.