Maren Lerfald , Linn Marita Hagen , Ekaterina Zotcheva , Federico Palumbo , Audun Havnen , Linda Ernstsen
{"title":"COVID-19 封锁前后老年人的估计心肺功能水平和抗抑郁药物使用情况：HUNT4 特隆赫姆 70 岁以上研究的结果","authors":"Maren Lerfald , Linn Marita Hagen , Ekaterina Zotcheva , Federico Palumbo , Audun Havnen , Linda Ernstsen","doi":"10.1016/j.mhpa.2024.100631","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Cardiorespiratory fitness (CRF) refers to the capacity of the cardiovascular and respiratory system to process oxygen. CRF is associated with depressive symptoms and findings suggest that CRF decreased significantly in older adults during the COVID-19 pandemic. However, purchase of prescribed antidepressants before and after the pandemic lockdown by CRF level in older adults has not yet been described.</p></div><div><h3>Methods</h3><p>This longitudinal study included 1221 community-dwelling older adults ≥70 years old participating in the Norwegian HUNT4 Trondheim 70+ study (2018–2019). Data on estimated CRF (eCRF) were linked to the Norwegian Prescribed Drug Registry and utilized defined daily doses (DDDs) of antidepressants from January 2019 throughout December 2021. Paired <em>t</em>-tests were performed to assess changes in DDDs before and after the Norwegian COVID-19 lockdown in March 2020.</p></div><div><h3>Results</h3><p>Participants had a mean (<em>M</em>) and standard deviation (<em>SD</em>) age of 76.5 (5.2) years, 53.6% were women. In the total sample, the results showed a significant rise in purchase of antidepressants from before (<em>M</em> = 1.25, <em>SD</em> = 7.17) compared to after the lockdown (<em>M</em> = 1.52, <em>SD</em> = 7.86); <em>t</em> (1220) = −2.47, <em>p</em> = 0.014). The number of participants purchasing antidepressants also increased in the total sample and within each of the eCRF groups. In the different eCRF groups, only individuals in the highest eCRF tertile showed a significant higher purchase of antidepressants after the lockdown (<em>M</em> = 1.44, <em>SD</em> = 6.65); t (413) = −2.63, <em>p</em> = 0.009) compared to the year before (<em>M</em> = 0.99, <em>SD</em> = 5.21).</p></div><div><h3>Conclusions</h3><p>Compared to before the COVID-19 pandemic lockdown, the utilization of antidepressants increased in community-dwelling older adults, with the steepest increase observed among those with the highest eCRF levels.</p></div>","PeriodicalId":51589,"journal":{"name":"Mental Health and Physical Activity","volume":"27 ","pages":"Article 100631"},"PeriodicalIF":2.3000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1755296624000577/pdfft?md5=ec07f0b77e430dba1dd26cffa9f1908b&pid=1-s2.0-S1755296624000577-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Estimated cardiorespiratory fitness level and utilization of antidepressants among older adults before and after the COVID-19 lockdown: Findings from the HUNT4 Trondheim 70+ study\",\"authors\":\"Maren Lerfald , Linn Marita Hagen , Ekaterina Zotcheva , Federico Palumbo , Audun Havnen , Linda Ernstsen\",\"doi\":\"10.1016/j.mhpa.2024.100631\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Cardiorespiratory fitness (CRF) refers to the capacity of the cardiovascular and respiratory system to process oxygen. CRF is associated with depressive symptoms and findings suggest that CRF decreased significantly in older adults during the COVID-19 pandemic. However, purchase of prescribed antidepressants before and after the pandemic lockdown by CRF level in older adults has not yet been described.</p></div><div><h3>Methods</h3><p>This longitudinal study included 1221 community-dwelling older adults ≥70 years old participating in the Norwegian HUNT4 Trondheim 70+ study (2018–2019). Data on estimated CRF (eCRF) were linked to the Norwegian Prescribed Drug Registry and utilized defined daily doses (DDDs) of antidepressants from January 2019 throughout December 2021. Paired <em>t</em>-tests were performed to assess changes in DDDs before and after the Norwegian COVID-19 lockdown in March 2020.</p></div><div><h3>Results</h3><p>Participants had a mean (<em>M</em>) and standard deviation (<em>SD</em>) age of 76.5 (5.2) years, 53.6% were women. In the total sample, the results showed a significant rise in purchase of antidepressants from before (<em>M</em> = 1.25, <em>SD</em> = 7.17) compared to after the lockdown (<em>M</em> = 1.52, <em>SD</em> = 7.86); <em>t</em> (1220) = −2.47, <em>p</em> = 0.014). The number of participants purchasing antidepressants also increased in the total sample and within each of the eCRF groups. In the different eCRF groups, only individuals in the highest eCRF tertile showed a significant higher purchase of antidepressants after the lockdown (<em>M</em> = 1.44, <em>SD</em> = 6.65); t (413) = −2.63, <em>p</em> = 0.009) compared to the year before (<em>M</em> = 0.99, <em>SD</em> = 5.21).</p></div><div><h3>Conclusions</h3><p>Compared to before the COVID-19 pandemic lockdown, the utilization of antidepressants increased in community-dwelling older adults, with the steepest increase observed among those with the highest eCRF levels.</p></div>\",\"PeriodicalId\":51589,\"journal\":{\"name\":\"Mental Health and Physical Activity\",\"volume\":\"27 \",\"pages\":\"Article 100631\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-09-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1755296624000577/pdfft?md5=ec07f0b77e430dba1dd26cffa9f1908b&pid=1-s2.0-S1755296624000577-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Mental Health and Physical Activity\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1755296624000577\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mental Health and Physical Activity","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1755296624000577","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}
Estimated cardiorespiratory fitness level and utilization of antidepressants among older adults before and after the COVID-19 lockdown: Findings from the HUNT4 Trondheim 70+ study
Background
Cardiorespiratory fitness (CRF) refers to the capacity of the cardiovascular and respiratory system to process oxygen. CRF is associated with depressive symptoms and findings suggest that CRF decreased significantly in older adults during the COVID-19 pandemic. However, purchase of prescribed antidepressants before and after the pandemic lockdown by CRF level in older adults has not yet been described.
Methods
This longitudinal study included 1221 community-dwelling older adults ≥70 years old participating in the Norwegian HUNT4 Trondheim 70+ study (2018–2019). Data on estimated CRF (eCRF) were linked to the Norwegian Prescribed Drug Registry and utilized defined daily doses (DDDs) of antidepressants from January 2019 throughout December 2021. Paired t-tests were performed to assess changes in DDDs before and after the Norwegian COVID-19 lockdown in March 2020.
Results
Participants had a mean (M) and standard deviation (SD) age of 76.5 (5.2) years, 53.6% were women. In the total sample, the results showed a significant rise in purchase of antidepressants from before (M = 1.25, SD = 7.17) compared to after the lockdown (M = 1.52, SD = 7.86); t (1220) = −2.47, p = 0.014). The number of participants purchasing antidepressants also increased in the total sample and within each of the eCRF groups. In the different eCRF groups, only individuals in the highest eCRF tertile showed a significant higher purchase of antidepressants after the lockdown (M = 1.44, SD = 6.65); t (413) = −2.63, p = 0.009) compared to the year before (M = 0.99, SD = 5.21).
Conclusions
Compared to before the COVID-19 pandemic lockdown, the utilization of antidepressants increased in community-dwelling older adults, with the steepest increase observed among those with the highest eCRF levels.
期刊介绍：
The aims of Mental Health and Physical Activity will be: (1) to foster the inter-disciplinary development and understanding of the mental health and physical activity field; (2) to develop research designs and methods to advance our understanding; (3) to promote the publication of high quality research on the effects of physical activity (interventions and a single session) on a wide range of dimensions of mental health and psychological well-being (eg, depression, anxiety and stress responses, mood, cognitive functioning and neurological disorders, such as dementia, self-esteem and related constructs, psychological aspects of quality of life among people with physical and mental illness, sleep, addictive disorders, eating disorders), from both efficacy and effectiveness trials;
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