{"title":"用于治疗压力性尿失禁的 Macroplastique® 显示出 PET-avid 尿道病变:病例报告","authors":"Christine Herforth, Philippe E. Zimmern","doi":"10.1016/j.crwh.2024.e00649","DOIUrl":null,"url":null,"abstract":"<div><p>Macroplastique® is a periurethral bulking agent used for the treatment of female stress urinary incontinence. It is composed of polydimethylsiloxane macroparticles suspended in a polyvinylpyrolidone carrier to allow injection. The patient in this case report had increased 18F-FDG avidity on PET scan at the site of prior Macroplastique® injection. This avidity was likely due to a local inflammatory response and did not represent an occult malignancy. Keen clinical judgement is necessary when this PET-avid area is demonstrated in women with prior bulking therapy as this is an incidental benign finding that does not require further invasive management.</p></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"43 ","pages":"Article e00649"},"PeriodicalIF":0.7000,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214911224000705/pdfft?md5=dae6611b2f06d0d86cf9673075ebeaf9&pid=1-s2.0-S2214911224000705-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Macroplastique® for stress urinary incontinence lights up as a PET-avid urethral lesion: A case report\",\"authors\":\"Christine Herforth, Philippe E. Zimmern\",\"doi\":\"10.1016/j.crwh.2024.e00649\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Macroplastique® is a periurethral bulking agent used for the treatment of female stress urinary incontinence. It is composed of polydimethylsiloxane macroparticles suspended in a polyvinylpyrolidone carrier to allow injection. The patient in this case report had increased 18F-FDG avidity on PET scan at the site of prior Macroplastique® injection. This avidity was likely due to a local inflammatory response and did not represent an occult malignancy. Keen clinical judgement is necessary when this PET-avid area is demonstrated in women with prior bulking therapy as this is an incidental benign finding that does not require further invasive management.</p></div>\",\"PeriodicalId\":9657,\"journal\":{\"name\":\"Case Reports in Women's Health\",\"volume\":\"43 \",\"pages\":\"Article e00649\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2024-09-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2214911224000705/pdfft?md5=dae6611b2f06d0d86cf9673075ebeaf9&pid=1-s2.0-S2214911224000705-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Women's Health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214911224000705\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Women's Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214911224000705","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
Macroplastique® 是一种尿道周围膨大剂,用于治疗女性压力性尿失禁。它由悬浮在聚乙烯吡咯烷酮载体中的聚二甲基硅氧烷大颗粒组成,便于注射。本病例报告中的患者曾在注射 Macroplastique® 的部位进行 PET 扫描,结果发现 18F-FDG 反应性增高。这种嗜性可能是由于局部炎症反应引起的,并不代表隐性恶性肿瘤。当曾接受过膨体治疗的妇女出现这种正电子发射计算机断层扫描(PET)阳性区域时,有必要进行审慎的临床判断,因为这是一种偶然的良性发现,不需要进一步的侵入性治疗。
Macroplastique® for stress urinary incontinence lights up as a PET-avid urethral lesion: A case report
Macroplastique® is a periurethral bulking agent used for the treatment of female stress urinary incontinence. It is composed of polydimethylsiloxane macroparticles suspended in a polyvinylpyrolidone carrier to allow injection. The patient in this case report had increased 18F-FDG avidity on PET scan at the site of prior Macroplastique® injection. This avidity was likely due to a local inflammatory response and did not represent an occult malignancy. Keen clinical judgement is necessary when this PET-avid area is demonstrated in women with prior bulking therapy as this is an incidental benign finding that does not require further invasive management.