波浪导航：了解从童年到成年的血压振幅和节律变化

IF 2.7 4区医学 Q2 PERIPHERAL VASCULAR DISEASE

Journal of Human Hypertension Pub Date : 2024-09-09 DOI:10.1038/s41371-024-00953-y

Nazar Mohd Azahar, Mohamad Rodi Isa, Mizuki Ohashi, Yuichiro Yano

引用次数: 0

摘要

昼夜节律调节个人的血压（BP）和心率。昼夜节律与心血管生理和疾病密切相关。昼夜节律的任何异常都可能导致睡眠问题、多种不良心血管事件[1]、心肾衰竭和心血管死亡风险增加[2]。这种昼夜节律机制，如清醒或睡眠、自主神经系统周期和松果体褪黑激素合成，是调节 24 小时血压曲线的因素[3]。了解它们的作用可为针对昼夜节律血压失调和高血压的定制治疗铺平道路[2]。儿童期和成年期的昼夜节律血压对于早期诊断心血管疾病和避免并发症至关重要[4]。从童年到成年，我们的身体经历了一系列显著的变化。在这些变化中，血压节律振幅和百分比节律变化的微妙而重要的变化在塑造我们的心血管健康方面发挥着重要作用。血压节律振幅是指余弦曲线的最高值与血压中线节律估计统计量（BP mesor）之间的距离[5]。血压节律振幅代表 24 小时内从血压峰值水平到平均血压水平之间的范围。血压节律振幅升高意味着 24 小时内最高血压读数与血压中线之间存在巨大差异。这种情况通常与血压下降模式和夜间血压水平较低有关。在儿童时期，随着心血管系统的成熟，这种节律振幅会逐渐减弱。随着年龄的增长，脉搏振幅增大，影响颈动脉、桡动脉和股动脉[6]。收缩压和舒张压轨迹最高的儿童（即早期血压高并持续升高）在成年早期出现血压升高的风险明显更高[7]。与血压轨迹相似，血压节律振幅也显示出预测未来高血压和心血管事件的潜力[8]。这些发现意味着，儿童和青少年时期的血压可预测成年后血压升高的发生。另一方面，较低百分比的节律变化意味着心跳节律减弱[9]。心脏的节律是由微妙的电信号相互作用协调而成的，在儿童时期，它经历了一个微调的过程。从童年到青春期的转变以心率下降为标志，反映了心血管系统的成熟。这一转变表明心脏的效率更高，能够更精确、更省力地泵送血液。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Navigating the waves: understanding blood pressure amplitude and rhythm changes from childhood to adulthood

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Navigating the waves: understanding blood pressure amplitude and rhythm changes from childhood to adulthood

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来源期刊

Journal of Human Hypertension 医学-外周血管病

CiteScore

5.20

自引率

3.70%

发文量

126

审稿时长

6-12 weeks

期刊介绍： Journal of Human Hypertension is published monthly and is of interest to health care professionals who deal with hypertension (specialists, internists, primary care physicians) and public health workers. We believe that our patients benefit from robust scientific data that are based on well conducted clinical trials. We also believe that basic sciences are the foundations on which we build our knowledge of clinical conditions and their management. Towards this end, although we are primarily a clinical based journal, we also welcome suitable basic sciences studies that promote our understanding of human hypertension. The journal aims to perform the dual role of increasing knowledge in the field of high blood pressure as well as improving the standard of care of patients. The editors will consider for publication all suitable papers dealing directly or indirectly with clinical aspects of hypertension, including but not limited to epidemiology, pathophysiology, therapeutics and basic sciences involving human subjects or tissues. We also consider papers from all specialties such as ophthalmology, cardiology, nephrology, obstetrics and stroke medicine that deal with the various aspects of hypertension and its complications.