通过烯烃的光诱导自由基级联氟烷基化/环化合成萘酮

IF 2.8 4区化学 Q1 CHEMISTRY, ORGANIC

Asian Journal of Organic Chemistry Pub Date : 2024-09-11 DOI:10.1002/ajoc.202400354

Xiaohu Yang, Chunmei Yang, Xiaoqing Wan, Wen-Chao Yang, Hegui Fang, Wenchao Yang

{"title":"通过烯烃的光诱导自由基级联氟烷基化/环化合成萘酮","authors":"Xiaohu Yang, Chunmei Yang, Xiaoqing Wan, Wen-Chao Yang, Hegui Fang, Wenchao Yang","doi":"10.1002/ajoc.202400354","DOIUrl":null,"url":null,"abstract":"Herein, we report a photoredox‐catalyzed fluoroalkylation of activated alkenes via fluorinated alkyl‐centered radical induced radical addition/annulation/SET/deprotonation in a domino fashion using 4CzIPN as photocatalyst. The protocol features room temperature, transition metal free, high yields and simple operation, affording a facile and efficient strategy to access fluorine‐containing naphthalenone.","PeriodicalId":130,"journal":{"name":"Asian Journal of Organic Chemistry","volume":"64 1","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis of Naphthalenones via Photo‐Induced Radical Cascade Fluoroalkylation/Cyclization of Alkenes\",\"authors\":\"Xiaohu Yang, Chunmei Yang, Xiaoqing Wan, Wen-Chao Yang, Hegui Fang, Wenchao Yang\",\"doi\":\"10.1002/ajoc.202400354\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Herein, we report a photoredox‐catalyzed fluoroalkylation of activated alkenes via fluorinated alkyl‐centered radical induced radical addition/annulation/SET/deprotonation in a domino fashion using 4CzIPN as photocatalyst. The protocol features room temperature, transition metal free, high yields and simple operation, affording a facile and efficient strategy to access fluorine‐containing naphthalenone.\",\"PeriodicalId\":130,\"journal\":{\"name\":\"Asian Journal of Organic Chemistry\",\"volume\":\"64 1\",\"pages\":\"\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2024-09-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Journal of Organic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1002/ajoc.202400354\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1002/ajoc.202400354","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}

引用次数: 0

摘要

在此，我们报告了以 4CzIPN 为光催化剂，通过氟化烷基中心自由基诱导的自由基加成/annulation/SET/去质子化反应，以多米诺方式对活化烯进行光氧化催化氟烷基化反应。该方案具有室温、不含过渡金属、产率高、操作简单等特点，为获得含氟萘酮提供了一种简便高效的策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Synthesis of Naphthalenones via Photo‐Induced Radical Cascade Fluoroalkylation/Cyclization of Alkenes

Herein, we report a photoredox‐catalyzed fluoroalkylation of activated alkenes via fluorinated alkyl‐centered radical induced radical addition/annulation/SET/deprotonation in a domino fashion using 4CzIPN as photocatalyst. The protocol features room temperature, transition metal free, high yields and simple operation, affording a facile and efficient strategy to access fluorine‐containing naphthalenone.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Asian Journal of Organic Chemistry CHEMISTRY, ORGANIC-

CiteScore

4.70

自引率

3.70%

发文量

372

期刊介绍： Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC) The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.