利用热处理大肠杆菌的电化学信号评估具有不同抗菌机制的抗生素的抗菌活性

IF 2.7 3区化学 Q2 CHEMISTRY, ANALYTICAL

Electroanalysis Pub Date : 2024-08-23 DOI:10.1002/elan.202400161

Jiaqi Fu, Jincheng Du, Ting Hou, Zhong Wang, Liyuan Sui, Jinlian Li, Yanli Zhao, Ximing Cui, Wu Dongmei

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引用次数: 0

摘要

以嘌呤为指示剂的电化学方法可能是一种很有前途的抗生素活性检测新方法。然而，传统的电化学检测方法（S-LSV）需要较长的嘌呤积累时间，且信号强度较低。对细菌样品进行高温处理可大大提高信号强度和检测速度。然而，这一过程也可能影响细菌的结构和新陈代谢。要确定电化学信号如何响应抗生素的抗菌活性，还需要进一步的研究。本文采用基于热处理大肠杆菌（E. coli，H-LSV）的电化学检测方法来研究抗生素抗菌活性对细菌的影响。

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Evaluation of the antibacterial activity of antibiotics with different antibacterial mechanisms using electrochemical signals of heat‐treated Escherichia coli

Electrochemistry with purines as indicators may be a promising new method for antibiotic activity testing. However, the traditional electrochemical detection method (S‐LSV) requires a long accumulation time for purines and has low signal intensity. High‐temperature treatment of bacterial samples may significantly enhance the signal intensity and speed of detection. However, this process may also impact the structure and metabolism of bacteria. Further research is necessary to determine how electrochemical signals respond to antibiotic antibacterial activity. In this paper, the electrochemical detection method based on heat‐treated Escherichia coli ( E. coli, H‐LSV) was used to investigate the

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来源期刊

Electroanalysis 化学-电化学

CiteScore

6.00

自引率

3.30%

发文量

222

审稿时长

2.4 months

期刊介绍： Electroanalysis is an international, peer-reviewed journal covering all branches of electroanalytical chemistry, including both fundamental and application papers as well as reviews dealing with new electrochemical sensors and biosensors, nanobioelectronics devices, analytical voltammetry, potentiometry, new electrochemical detection schemes based on novel nanomaterials, fuel cells and biofuel cells, and important practical applications. Serving as a vital communication link between the research labs and the field, Electroanalysis helps you to quickly adapt the latest innovations into practical clinical, environmental, food analysis, industrial and energy-related applications. Electroanalysis provides the most comprehensive coverage of the field and is the number one source for information on electroanalytical chemistry, electrochemical sensors and biosensors and fuel/biofuel cells.