基于分子印迹纳米粒子的聚合物（丙烯酰胺-N-乙烯基咪唑）/纳菲欧薄膜改性丝网印刷电极系统，用于快速测定血红蛋白

IF 2.7 3区化学 Q2 CHEMISTRY, ANALYTICAL

Electroanalysis Pub Date : 2024-08-29 DOI:10.1002/elan.202400274

Hilal Özçelik, Esra Yaşar, Timuçin Güner, Emre Dokuzparmak, Koray Şarkaya, Sinan Akgöl

{"title":"基于分子印迹纳米粒子的聚合物（丙烯酰胺-N-乙烯基咪唑）/纳菲欧薄膜改性丝网印刷电极系统，用于快速测定血红蛋白","authors":"Hilal Özçelik, Esra Yaşar, Timuçin Güner, Emre Dokuzparmak, Koray Şarkaya, Sinan Akgöl","doi":"10.1002/elan.202400274","DOIUrl":null,"url":null,"abstract":"In medical diagnostics, variations in hemoglobin levels can reveal a variety of prevalent health conditions. Abnormal hemoglobin is known to be connected with diseases like anemia, diabetes, hematemesis, hematuria, and hemoglobinuria. Consequently, there is a significant demand for advanced detection technologies and precise methodologies to accurately track and assess hemoglobin levels. This study demonstrates the potential of a novel molecularly imprinted nanoparticle‐based sensor system to rapidly analyze hemoglobin levels without the need for a laboratory environment. Hemoglobin imprinted‐poly(acrylamide‐ co‐vinyl imidazole) [Hb‐imp‐p(AAm‐ co‐VIM)] nanoparticles with high affinity and selectivity for hemoglobin were synthesized and loaded onto the","PeriodicalId":162,"journal":{"name":"Electroanalysis","volume":"179 1","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Molecularly Imprinted Nanoparticle‐Based polymer (Acrylamide‐N‐Vinyl imidazol)/Nafion Film Modified Screen‐Printed Electrode System for Rapid Determination of Hemoglobin\",\"authors\":\"Hilal Özçelik, Esra Yaşar, Timuçin Güner, Emre Dokuzparmak, Koray Şarkaya, Sinan Akgöl\",\"doi\":\"10.1002/elan.202400274\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In medical diagnostics, variations in hemoglobin levels can reveal a variety of prevalent health conditions. Abnormal hemoglobin is known to be connected with diseases like anemia, diabetes, hematemesis, hematuria, and hemoglobinuria. Consequently, there is a significant demand for advanced detection technologies and precise methodologies to accurately track and assess hemoglobin levels. This study demonstrates the potential of a novel molecularly imprinted nanoparticle‐based sensor system to rapidly analyze hemoglobin levels without the need for a laboratory environment. Hemoglobin imprinted‐poly(acrylamide‐ co‐vinyl imidazole) [Hb‐imp‐p(AAm‐ co‐VIM)] nanoparticles with high affinity and selectivity for hemoglobin were synthesized and loaded onto the\",\"PeriodicalId\":162,\"journal\":{\"name\":\"Electroanalysis\",\"volume\":\"179 1\",\"pages\":\"\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2024-08-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Electroanalysis\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1002/elan.202400274\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Electroanalysis","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1002/elan.202400274","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}

引用次数: 0

摘要

在医学诊断中，血红蛋白水平的变化可以揭示各种普遍的健康状况。众所周知，血红蛋白异常与贫血、糖尿病、吐血、血尿和血红蛋白尿等疾病有关。因此，对先进检测技术和精确方法的需求很大，以准确跟踪和评估血红蛋白水平。本研究展示了一种基于分子印迹纳米粒子的新型传感器系统在无需实验室环境的情况下快速分析血红蛋白水平的潜力。研究人员合成了对血红蛋白具有高亲和力和选择性的血红蛋白印迹聚（丙烯酰胺-共-乙烯基咪唑）[Hb-imp-p(AAm-共-VIM)]纳米粒子，并将其装载到了胰岛素传感器上。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Molecularly Imprinted Nanoparticle‐Based polymer (Acrylamide‐N‐Vinyl imidazol)/Nafion Film Modified Screen‐Printed Electrode System for Rapid Determination of Hemoglobin

In medical diagnostics, variations in hemoglobin levels can reveal a variety of prevalent health conditions. Abnormal hemoglobin is known to be connected with diseases like anemia, diabetes, hematemesis, hematuria, and hemoglobinuria. Consequently, there is a significant demand for advanced detection technologies and precise methodologies to accurately track and assess hemoglobin levels. This study demonstrates the potential of a novel molecularly imprinted nanoparticle‐based sensor system to rapidly analyze hemoglobin levels without the need for a laboratory environment. Hemoglobin imprinted‐poly(acrylamide‐ co‐vinyl imidazole) [Hb‐imp‐p(AAm‐ co‐VIM)] nanoparticles with high affinity and selectivity for hemoglobin were synthesized and loaded onto the

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Electroanalysis 化学-电化学

CiteScore

6.00

自引率

3.30%

发文量

222

审稿时长

2.4 months

期刊介绍： Electroanalysis is an international, peer-reviewed journal covering all branches of electroanalytical chemistry, including both fundamental and application papers as well as reviews dealing with new electrochemical sensors and biosensors, nanobioelectronics devices, analytical voltammetry, potentiometry, new electrochemical detection schemes based on novel nanomaterials, fuel cells and biofuel cells, and important practical applications. Serving as a vital communication link between the research labs and the field, Electroanalysis helps you to quickly adapt the latest innovations into practical clinical, environmental, food analysis, industrial and energy-related applications. Electroanalysis provides the most comprehensive coverage of the field and is the number one source for information on electroanalytical chemistry, electrochemical sensors and biosensors and fuel/biofuel cells.