设计用于无标记检测血液成分的高效表面等离子体共振生物传感器

IF 3.3 4区 物理与天体物理 Q2 CHEMISTRY, PHYSICAL
Trupti Kamani, Abdullah Baz, Shobhit K. Patel
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引用次数: 0

摘要

光学折射率生物传感器是用于评估血浆、白细胞、血红蛋白、红细胞和糖尿病等各种血液成分的易感设备。这些生物传感器在环境监测、制药、生物医学研究和医疗保健等多个领域发挥着至关重要的作用。这些设备旨在通过将特定生物分子或化合物的相互作用转化为可测量的信号来检测它们。本手稿推荐了一种分离式循环折射率生物传感器(DCRIB),用于测定五种不同的血液成分。血浆的灵敏度(S)最高为 1400 nm/RIU,红细胞的品质因数(QF)最高为 769.23,红细胞的优度(FOM)最高为 540.43,糖尿病细胞的最小测定极限为 0.0004895,红细胞的测定范围最高为 1225.43。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Design of an Efficient Surface Plasmon Resonance Biosensor for Label-Free Detection of Blood Components

Design of an Efficient Surface Plasmon Resonance Biosensor for Label-Free Detection of Blood Components

Optical refractive index biosensors are susceptible devices for the assessment of various blood components like blood plasma, WBCs, hemoglobin, RBCs, and diabetes mellitus. These biosensors play a crucial role in various fields, including environmental monitoring, pharmaceuticals, biomedical research, and health care. These devices are designed to detect specific biological molecules or chemical compounds by converting their interactions into measurable signals. This manuscript recommends a detached cyclic refractive index biosensor (DCRIB) for the determination of five respective kinds of blood components. The high-rise sensitivity (S) count of 1400 nm/RIU has been noticed for blood plasma, the high-rise quality factor (QF) count is 769.23 for RBCs, the high-rise figure of merit (FOM) count is 540.43 for RBCs, and the minimum determination limit count is 0.0004895 for diabetes cell, along with a high-rise determination range count of 1225.43 for RBCs.

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来源期刊
Plasmonics
Plasmonics 工程技术-材料科学:综合
CiteScore
5.90
自引率
6.70%
发文量
164
审稿时长
2.1 months
期刊介绍: Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons. Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.
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