罗丹明-苯并噻唑-噻吩：同时检测 Hg2+ 和 Cu2+ 的三角形分子工具

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal Pub Date : 2024-08-31 DOI:10.1016/j.microc.2024.111549

Brian Musikavanhu, Xin Huang, Quanhong Ma, Zhaoli Xue, Lei Feng, Long Zhao

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引用次数: 0

摘要

设计了一种新型的罗丹明-苯并噻唑荧光化学传感器，该传感器与噻吩单元桥接，用于开启式检测汞和铜。值得注意的发现包括：令人印象深刻的低检测限（汞为 0.007 μM，铜为 0.013 μM）、涉及螺内酰胺环打开和水解裂解的确定传感机制、两种金属离子一致的 1:1 结合配比以及约 6 的最佳 pH 值。通过在 HeLa 细胞和斑马鱼中的成功应用，以及在各种水样中的有效分析回收，证明了该传感器的实用性。这项工作为环境和生物应用提供了一种高灵敏度、多功能的化学传感器，从而推动了该领域的发展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Rhodamine-benzothiazole-thiophene: A triangular molecular tool for simultaneous detection of Hg2+ and Cu2+

A novel rhodamine-benzothiazole fluorescent chemosensor, bridged with a thiophene unit, is designed for the turn-on detection of Hg and Cu. Noteworthy findings include impressively low limits of detection (0.007 μM for Hg and 0.013 μM for Cu), a determined sensing mechanism involving spirolactam ring opening and hydrolytic cleavage, consistent 1:1 binding stoichiometry for both metal ions and an optimal pH of around 6. The sensor’s practical applicability is demonstrated through successful implementation in HeLa cells and zebrafish, along with effective analyte recovery in various water samples. This work advances the field by providing a highly sensitive and versatile chemosensor for environmental and biological applications.

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来源期刊

Microchemical Journal 化学-分析化学

CiteScore

8.70

自引率

8.30%

发文量

1131

审稿时长

1.9 months

期刊介绍： The Microchemical Journal is a peer reviewed journal devoted to all aspects and phases of analytical chemistry and chemical analysis. The Microchemical Journal publishes articles which are at the forefront of modern analytical chemistry and cover innovations in the techniques to the finest possible limits. This includes fundamental aspects, instrumentation, new developments, innovative and novel methods and applications including environmental and clinical field. Traditional classical analytical methods such as spectrophotometry and titrimetry as well as established instrumentation methods such as flame and graphite furnace atomic absorption spectrometry, gas chromatography, and modified glassy or carbon electrode electrochemical methods will be considered, provided they show significant improvements and novelty compared to the established methods.