中国老年人的多病症与认知功能之间的关系：基于倾向得分匹配法

IF 3 3区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Frontiers in Public Health Pub Date : 2024-09-12 DOI:10.3389/fpubh.2024.1422000

Yumeng Zhang, Xiaoli Yuan, Zhixia Jiang, Rujun Hu, Heting Liang, Qingyun Mao, Yan Xiong, Jiabi Zhang, Mi Liu

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引用次数: 0

摘要

方法在贵州省遵义市的 7 家医疗机构、3 个社区和 5 家养老院，通过便利抽样对 60 岁及以上的老年人进行横断面调查。收集的数据包括一般信息、健康相关信息和迷你精神状态检查（MMSE）得分。通过PSM对变量进行混杂因素控制，分析多病与非多病老年人认知能力的差异。结果共有14175名受访者参与了这项研究，受访者的平均年龄为（71.26 ± 7.1）岁，其中7170名受访者（50.58%）为男性，7005名受访者（49.42%）为女性，5482名受访者（38.67%）接受了认知能力下降筛查。经过 PSM 后，逻辑回归分析显示，多病是认知能力下降的风险因素（OR = 1.392，95% CI = 1.271-1.525，p &pamp;lt;0.001）。研究结果表明，在相同年龄段，患有多种疾病的老年人认知能力下降的风险总是高于未患有多种疾病的老年人。年龄、性别、婚姻状况、教育程度、月收入、饮酒状况、社会活动参与度和运动量是老年人认知能力下降的影响因素（p <0.05）。结论罹患多种疾病的老年人认知能力下降的风险高于未罹患多种疾病的老年人，因此政府应加强对老年人罹患多种疾病的预防和治疗，以进一步保护老年人的认知能力。

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The relationship between multimorbidity and cognitive function in older Chinese adults: based on propensity score matching

ObjectiveThe goal of this study was to further validate the effect of multimorbidity on cognitive performance in older adults after controlling for confounders using propensity score matching (PSM).MethodsA cross-sectional survey of older adult people aged 60 years or older selected by convenience sampling was conducted in seven medical institutions, three communities, and five nursing homes in Zunyi City, Guizhou Province. The data collected included general information, health-related information, and Mini-Mental State Examination (MMSE) scores. Variables were controlled for confounders by PSM to analyze differences in cognitive ability between multimorbidity and nonmultimorbidity older adults. Logistic regression and multivariate-adjusted restricted cubic spline (RCS) curves for matched samples were used to assess the relationship between multimorbidity and cognitive decline.ResultsA total of 14,175 respondents were enrolled, and the mean age of the participants included in this study was 71.26 ± 7.1 years, including 7,170 (50. 58%) of the participants were males, 7,005 (49.42%) were females, and 5,482 participants (38.67%) were screened for cognitive decline. After PSM, logistic regression analysis revealed that multimorbidity was a risk factor for cognitive decline (OR = 1.392, 95% CI = 1.271–1.525, p < 0.001). The RCS show that the risk of cognitive decline is always greater in older adults with multimorbidity than in older adults without multimorbidity at the same age. Age, sex, marital status, educational level, monthly income, drinking status, participation in social activities, and exercise were influential factors for cognitive decline in older adults (p < 0.05). The incidence of cognitive decline in older adults with multimorbidity was also greater than that in older adults with one chronic disease (p < 0.001).ConclusionThe risk of cognitive decline in older adults with multimorbidity is greater than that in older adults without multimorbidity; therefore, the government should strengthen the prevention and treatment of multimorbidity in older adults to further protect their cognitive abilities.

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来源期刊

Frontiers in Public Health Medicine-Public Health, Environmental and Occupational Health

CiteScore

4.80

自引率

7.70%

发文量

4469

审稿时长

14 weeks

期刊介绍： Frontiers in Public Health is a multidisciplinary open-access journal which publishes rigorously peer-reviewed research and is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians, policy makers and the public worldwide. The journal aims at overcoming current fragmentation in research and publication, promoting consistency in pursuing relevant scientific themes, and supporting finding dissemination and translation into practice. Frontiers in Public Health is organized into Specialty Sections that cover different areas of research in the field. Please refer to the author guidelines for details on article types and the submission process.