环境污染物和坏虫子狼狈为奸

IF 14.3 1区 医学 Q1 ONCOLOGY
Dingjiacheng Jia, Shujie Chen
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引用次数: 0

摘要

坏细菌 "会改变环境污染物的毒物动力学,从而加剧化学诱导的肿瘤发生。最近,Roje 等人报告说,特定的肠道微生物群能将亚硝胺化合物代谢为有毒的氧化产物,从而加剧膀胱癌的发展和恶化。这些发现对通过肠道微生物群干预肿瘤具有重要意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Environmental pollutants and bad bugs work hand in glove

‘Bad bacteria’ could alter the toxicokinetics of environmental pollutants, thereby exacerbating chemically induced tumorigenesis. Recently, Roje et al. reported that specific gut microbiota can metabolize nitrosamine compounds to a toxic oxidation product, aggravating bladder cancer development and progression. These findings have important implications for tumor intervention through the gut microbiota.

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来源期刊
Trends in cancer
Trends in cancer Medicine-Oncology
CiteScore
28.50
自引率
0.50%
发文量
138
期刊介绍: Trends in Cancer, a part of the Trends review journals, delivers concise and engaging expert commentary on key research topics and cutting-edge advances in cancer discovery and medicine. Trends in Cancer serves as a unique platform for multidisciplinary information, fostering discussion and education for scientists, clinicians, policy makers, and patients & advocates.Covering various aspects, it presents opportunities, challenges, and impacts of basic, translational, and clinical findings, industry R&D, technology, innovation, ethics, and cancer policy and funding in an authoritative yet reader-friendly format.
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