汞基有机金属和配位化合物在医学应用方面的最新趋势

IF 4.1 3区 化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR
Fozia Maqsood, Sawsan S. Al-Rawi, Ahmad H. Ibrahim, Faisal Jamil, Ayesha Zafar, Muhammad Adnan Iqbal, Umar Sohail Shoukat, Mohammad Asad, Sami Ullah Zia, Farhan Ahmad, Muhammad Atif
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引用次数: 0

摘要

金属类药物在医疗领域,特别是抗菌疗法中的应用日新月异。Prontosil 和环丙沙星等化合物及其衍生物,如β-内酰胺类药物、氨基糖苷类药物、万古霉素、磷霉素以及四环素类药物,在预防细菌和真菌感染方面发挥着至关重要的作用。微生物抗药性的日益普遍促使人们使用金属复合物来对付真菌和细菌菌株。以汞为基础的络合物因其不同寻常的特性和反应性而闻名,最近在医学领域受到了广泛关注。此外,希夫碱络合物还被广泛用作抗真菌、抗细菌和抗癌药物,以及染料制造。本文讨论了目前利用汞化合物抗击真菌和细菌的进展,并提供了有关其功效和未来应用的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recent trends in medicinal applications of mercury based organometallic and coordination compounds
Metal-based drugs are finding new medical applications, particularly in antibacterial therapies. Compounds such as Prontosil and ciprofloxacin, as well as its derivatives such as beta-lactam drugs, aminoglycosides, vancomycin, fosfomycin, as well as tetracyclines, play critical roles in the prevention of bacterial and fungal infections. The increasing prevalence of microbial resistance is prompting the use of metal complexes to tackle fungal and bacterial strains. Mercury-based complexes, which are known for their unusual characteristics and reactivity, have received a lot of interest in the field of medicine recently. Additionally, Schiff base complexes are widely used as antifungal, antibacterial, and anticancer drugs, as well as in dye manufacturing. This article discusses current advances in the use of mercury compounds for combating fungus and bacteria, offering information on their efficacy and future applications.
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来源期刊
Reviews in Inorganic Chemistry
Reviews in Inorganic Chemistry 化学-分析化学
CiteScore
7.30
自引率
4.90%
发文量
20
审稿时长
1 months
期刊介绍: Reviews in Inorganic Chemistry (REVIC) is a quarterly, peer-reviewed journal that focuses on developments in inorganic chemistry. Technical reviews offer detailed synthesis protocols, reviews of methodology and descriptions of apparatus. Topics are treated from a synthetic, theoretical, or analytical perspective. The editors and the publisher are committed to high quality standards and rapid handling of the review and publication process. The journal publishes all aspects of solid-state, molecular and surface chemistry. Topics may be treated from a synthetic, theoretical, or analytical perspective. The editors and the publisher are commited to high quality standards and rapid handling of the review and publication process. Topics: -Main group chemistry- Transition metal chemistry- Coordination chemistry- Organometallic chemistry- Catalysis- Bioinorganic chemistry- Supramolecular chemistry- Ionic liquids
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