激光驱动电子源，适用于以超过 1010 Gy/s 的剂量率对生物细胞进行单次 Gy 级辐照

IF 2.4 3区物理与天体物理 Q1 Mathematics

Physical review. E Pub Date : 2024-09-12 DOI:10.1103/physreve.110.035204

C. A. McAnespie, P. Chaudhary, L. Calvin, M. J. V. Streeter, G. Nersysian, S. J. McMahon, K. M. Prise, G. Sarri

{"title":"激光驱动电子源，适用于以超过 1010 Gy/s 的剂量率对生物细胞进行单次 Gy 级辐照","authors":"C. A. McAnespie, P. Chaudhary, L. Calvin, M. J. V. Streeter, G. Nersysian, S. J. McMahon, K. M. Prise, G. Sarri","doi":"10.1103/physreve.110.035204","DOIUrl":null,"url":null,"abstract":"We report on the first systematic characterization of a tuneable laser-driven electron source capable of delivering Gy-scale doses in a duration of 10–20 ps in a single irradiation, thus reaching unprecedented dose rates in the range of <math xmlns=\"http://www.w3.org/1998/Math/MathML\"><mrow><msup><mn>10</mn><mn>10</mn></msup><mtext>–</mtext><msup><mn>10</mn><mn>12</mn></msup></mrow></math> Gy/s. Detailed characterization of the source indicates, in agreement with Monte Carlo simulations, dose delivery over cm-scale areas with a high degree of spatial uniformity. The results reported here confirm that a laser-driven source of this kind can be used for systematic studies of the response of biological cells to picosecond-scale radiation at ultrahigh dose rates.","PeriodicalId":20085,"journal":{"name":"Physical review. E","volume":null,"pages":null},"PeriodicalIF":2.4000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Laser-driven electron source suitable for single-shot Gy-scale irradiation of biological cells at dose rates exceeding 1010 Gy/s\",\"authors\":\"C. A. McAnespie, P. Chaudhary, L. Calvin, M. J. V. Streeter, G. Nersysian, S. J. McMahon, K. M. Prise, G. Sarri\",\"doi\":\"10.1103/physreve.110.035204\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We report on the first systematic characterization of a tuneable laser-driven electron source capable of delivering Gy-scale doses in a duration of 10–20 ps in a single irradiation, thus reaching unprecedented dose rates in the range of <math xmlns=\\\"http://www.w3.org/1998/Math/MathML\\\"><mrow><msup><mn>10</mn><mn>10</mn></msup><mtext>–</mtext><msup><mn>10</mn><mn>12</mn></msup></mrow></math> Gy/s. Detailed characterization of the source indicates, in agreement with Monte Carlo simulations, dose delivery over cm-scale areas with a high degree of spatial uniformity. The results reported here confirm that a laser-driven source of this kind can be used for systematic studies of the response of biological cells to picosecond-scale radiation at ultrahigh dose rates.\",\"PeriodicalId\":20085,\"journal\":{\"name\":\"Physical review. E\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2024-09-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physical review. E\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://doi.org/10.1103/physreve.110.035204\",\"RegionNum\":3,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Mathematics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physical review. E","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1103/physreve.110.035204","RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Mathematics","Score":null,"Total":0}

引用次数: 0

摘要

我们首次报道了一种可调激光驱动电子源的系统特性，这种电子源能够在 10-20 ps 的持续时间内提供 Gy 级剂量，从而达到前所未有的 1010-1012 Gy/s 剂量率。该源的详细特性表明，与蒙特卡洛模拟一致，在厘米级区域内的剂量传输具有高度的空间均匀性。本文报告的结果证实，这种激光驱动源可用于系统研究生物细胞对皮秒级超高剂量率辐射的反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Laser-driven electron source suitable for single-shot Gy-scale irradiation of biological cells at dose rates exceeding 1010 Gy/s

查看原文本刊更多论文

Laser-driven electron source suitable for single-shot Gy-scale irradiation of biological cells at dose rates exceeding 1010 Gy/s

We report on the first systematic characterization of a tuneable laser-driven electron source capable of delivering Gy-scale doses in a duration of 10–20 ps in a single irradiation, thus reaching unprecedented dose rates in the range of

10^{10} – 10^{12}

Gy/s. Detailed characterization of the source indicates, in agreement with Monte Carlo simulations, dose delivery over cm-scale areas with a high degree of spatial uniformity. The results reported here confirm that a laser-driven source of this kind can be used for systematic studies of the response of biological cells to picosecond-scale radiation at ultrahigh dose rates.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Physical review. E 物理-物理：流体与等离子体

CiteScore

4.60

自引率

16.70%

发文量

审稿时长

3.3 months

期刊介绍： Physical Review E (PRE), broad and interdisciplinary in scope, focuses on collective phenomena of many-body systems, with statistical physics and nonlinear dynamics as the central themes of the journal. Physical Review E publishes recent developments in biological and soft matter physics including granular materials, colloids, complex fluids, liquid crystals, and polymers. The journal covers fluid dynamics and plasma physics and includes sections on computational and interdisciplinary physics, for example, complex networks.