Min Liu, Jianning Ma, Kena Bao, Ye Gu, Jing Zhao, Dongmei Ren, Fang Zhu, Xiangdong Xu
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Results Univariate analysis results of demographic information, laboratory test results, and questionnaire survey data revealed that the differences in fatigue symptom, age, HDL, TG, and sleep quality were statistically significant (<jats:italic>p</jats:italic> = 0.006, <jats:italic>p</jats:italic> = 0.000, <jats:italic>p</jats:italic> = 0.019, <jats:italic>p</jats:italic> = 0.028, and <jats:italic>p</jats:italic> = 0.037, respectively). Logistic regression analysis showed that age, fatigue, and sleep quality were the influence factors for CI in CAD population (<jats:italic>p</jats:italic> = 0.000, <jats:italic>p</jats:italic> = 0.035, and <jats:italic>p</jats:italic> = 0.017). Conclusions Sleep quality, fatigue, and age were associated with the increased susceptibility of CI in CAD patients. Both CI state and its related factors were involved in the pathological process of CAD, these findings could offer additional information for the prevention and control of CAD.","PeriodicalId":19715,"journal":{"name":"Open Medicine","volume":"2 1","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sleep quality associate with the increased prevalence of cognitive impairment in coronary artery disease patients: A retrospective case–control study\",\"authors\":\"Min Liu, Jianning Ma, Kena Bao, Ye Gu, Jing Zhao, Dongmei Ren, Fang Zhu, Xiangdong Xu\",\"doi\":\"10.1515/med-2024-1034\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background The pathogenesis of cognitive impairment (CI) in coronary artery disease (CAD) patients is still unclear and numerous influence factors could affect the CI status. The current studies suggest that sleep quality and behavior pattern are significant influence factors associated with CAD susceptibility. Methods A total of 223 participants including 90 CAD patients with CI and 133 controls were enrolled into this retrospective study. Demographic information, laboratory test results, clinical diagnostic data, and questionnaire survey were collected to recognize the influencing factors of CI in CAD patients. Appropriate statistical methods are used to analyze these collected data. Results Univariate analysis results of demographic information, laboratory test results, and questionnaire survey data revealed that the differences in fatigue symptom, age, HDL, TG, and sleep quality were statistically significant (<jats:italic>p</jats:italic> = 0.006, <jats:italic>p</jats:italic> = 0.000, <jats:italic>p</jats:italic> = 0.019, <jats:italic>p</jats:italic> = 0.028, and <jats:italic>p</jats:italic> = 0.037, respectively). Logistic regression analysis showed that age, fatigue, and sleep quality were the influence factors for CI in CAD population (<jats:italic>p</jats:italic> = 0.000, <jats:italic>p</jats:italic> = 0.035, and <jats:italic>p</jats:italic> = 0.017). Conclusions Sleep quality, fatigue, and age were associated with the increased susceptibility of CI in CAD patients. Both CI state and its related factors were involved in the pathological process of CAD, these findings could offer additional information for the prevention and control of CAD.\",\"PeriodicalId\":19715,\"journal\":{\"name\":\"Open Medicine\",\"volume\":\"2 1\",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2024-09-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1515/med-2024-1034\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1515/med-2024-1034","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
背景 冠状动脉疾病(CAD)患者认知障碍(CI)的发病机制尚不清楚,有许多影响因素可能会影响认知障碍的状况。目前的研究表明,睡眠质量和行为模式是与 CAD 易感性相关的重要影响因素。方法 这项回顾性研究共纳入 223 名参与者,其中包括 90 名伴有 CI 的 CAD 患者和 133 名对照者。研究收集了人口统计学信息、实验室检测结果、临床诊断数据和问卷调查,以了解 CAD 患者 CI 的影响因素。研究采用适当的统计学方法对收集到的数据进行分析。结果 人口统计学信息、实验室检测结果和问卷调查数据的单变量分析结果显示,疲劳症状、年龄、高密度脂蛋白、总胆固醇和睡眠质量的差异具有统计学意义(分别为 p = 0.006、p = 0.000、p = 0.019、p = 0.028 和 p = 0.037)。逻辑回归分析表明,年龄、疲劳和睡眠质量是影响 CAD 患者 CI 的因素(p = 0.000、p = 0.035 和 p = 0.017)。结论 睡眠质量、疲劳和年龄与 CAD 患者的 CI 易感性增加有关。CI状态及其相关因素均参与了CAD的病理过程,这些发现可为CAD的预防和控制提供更多信息。
Sleep quality associate with the increased prevalence of cognitive impairment in coronary artery disease patients: A retrospective case–control study
Background The pathogenesis of cognitive impairment (CI) in coronary artery disease (CAD) patients is still unclear and numerous influence factors could affect the CI status. The current studies suggest that sleep quality and behavior pattern are significant influence factors associated with CAD susceptibility. Methods A total of 223 participants including 90 CAD patients with CI and 133 controls were enrolled into this retrospective study. Demographic information, laboratory test results, clinical diagnostic data, and questionnaire survey were collected to recognize the influencing factors of CI in CAD patients. Appropriate statistical methods are used to analyze these collected data. Results Univariate analysis results of demographic information, laboratory test results, and questionnaire survey data revealed that the differences in fatigue symptom, age, HDL, TG, and sleep quality were statistically significant (p = 0.006, p = 0.000, p = 0.019, p = 0.028, and p = 0.037, respectively). Logistic regression analysis showed that age, fatigue, and sleep quality were the influence factors for CI in CAD population (p = 0.000, p = 0.035, and p = 0.017). Conclusions Sleep quality, fatigue, and age were associated with the increased susceptibility of CI in CAD patients. Both CI state and its related factors were involved in the pathological process of CAD, these findings could offer additional information for the prevention and control of CAD.
期刊介绍:
Open Medicine is an open access journal that provides users with free, instant, and continued access to all content worldwide. The primary goal of the journal has always been a focus on maintaining the high quality of its published content. Its mission is to facilitate the exchange of ideas between medical science researchers from different countries. Papers connected to all fields of medicine and public health are welcomed. Open Medicine accepts submissions of research articles, reviews, case reports, letters to editor and book reviews.