用于增强电化学(N-(4-羟基苯基)乙酰胺)传感的生物纳米氧化银粒子

IF 0.9 4区 物理与天体物理 Q4 PHYSICS, CONDENSED MATTER
Syed Yaseen Ahmed, D. Bharathi, Paulson Emerson, A. Muthuvel, Wajeeha Sultana, Balu Mahendran Gunasekaran
{"title":"用于增强电化学(N-(4-羟基苯基)乙酰胺)传感的生物纳米氧化银粒子","authors":"Syed Yaseen Ahmed,&nbsp;D. Bharathi,&nbsp;Paulson Emerson,&nbsp;A. Muthuvel,&nbsp;Wajeeha Sultana,&nbsp;Balu Mahendran Gunasekaran","doi":"10.1134/S1063783424600638","DOIUrl":null,"url":null,"abstract":"<p>Nowadays, the identification of hepatotoxic compounds is necessary for clinical diagnosis as well as quantity management of their pharmaceutical formulations. In this study, silver oxide modified glassy carbon electrode synthesized using leaf extract of <i>Ocimum tenuiflorum</i> is adopted for sensing of (N-(4-hydroxyphenyl)acetamide). This drug molecules has regularly used pain killer that might cause liver injury under specific conditions. In addition, their physiochemical properties of bio-synthesized AgO nanoparticles have been examined with appropriate characterization techniques. Crystalline characteristic of AgO was non-destructively examined by the XRD-structural analysis. Structural examination claimed that the bioconstitutents of <i>Ocimum tenuiflorum</i> was effectively governs silver oxide formations from metal ions. The FT-IR vibrational assignments illustrate the AgO nanoparticles surface was influenced by some of the phytocompounds. Moreover, the overall particle’s uniformity and their distribution has been considerably controlled by the biomolecules. When oxidizing (N-(4-hydroxyphenyl)acetamide) in 0.1 M H<sub>2</sub>SO<sub>4</sub>, AgO NPs demonstrated superior electrocatalytic activity compared to bare SPE, and the separated oxidation peak potentials permitted simultaneous detection of the targets with broad linear ranges from 5 × 10<sup>–6</sup> to 3.4 × 10<sup>–6</sup> mol L<sup>–1</sup> low detection limit 8.5 × 10<sup>–6</sup> mol L<sup>–1</sup>, and outstanding precision and accuracy (S/N = 3). The approach has been effectively used to identify ACOP in pharmaceutical pills because AgO nanoparticles demonstrate good stability, reproducibility, and repeatability.</p>","PeriodicalId":731,"journal":{"name":"Physics of the Solid State","volume":null,"pages":null},"PeriodicalIF":0.9000,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Biogenic Silver Oxide Nanoparticles for Enhanced Electrochemical (N-(4-Hydroxyphenyl)Acetamide) Sensing\",\"authors\":\"Syed Yaseen Ahmed,&nbsp;D. Bharathi,&nbsp;Paulson Emerson,&nbsp;A. Muthuvel,&nbsp;Wajeeha Sultana,&nbsp;Balu Mahendran Gunasekaran\",\"doi\":\"10.1134/S1063783424600638\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Nowadays, the identification of hepatotoxic compounds is necessary for clinical diagnosis as well as quantity management of their pharmaceutical formulations. In this study, silver oxide modified glassy carbon electrode synthesized using leaf extract of <i>Ocimum tenuiflorum</i> is adopted for sensing of (N-(4-hydroxyphenyl)acetamide). This drug molecules has regularly used pain killer that might cause liver injury under specific conditions. In addition, their physiochemical properties of bio-synthesized AgO nanoparticles have been examined with appropriate characterization techniques. Crystalline characteristic of AgO was non-destructively examined by the XRD-structural analysis. Structural examination claimed that the bioconstitutents of <i>Ocimum tenuiflorum</i> was effectively governs silver oxide formations from metal ions. The FT-IR vibrational assignments illustrate the AgO nanoparticles surface was influenced by some of the phytocompounds. Moreover, the overall particle’s uniformity and their distribution has been considerably controlled by the biomolecules. When oxidizing (N-(4-hydroxyphenyl)acetamide) in 0.1 M H<sub>2</sub>SO<sub>4</sub>, AgO NPs demonstrated superior electrocatalytic activity compared to bare SPE, and the separated oxidation peak potentials permitted simultaneous detection of the targets with broad linear ranges from 5 × 10<sup>–6</sup> to 3.4 × 10<sup>–6</sup> mol L<sup>–1</sup> low detection limit 8.5 × 10<sup>–6</sup> mol L<sup>–1</sup>, and outstanding precision and accuracy (S/N = 3). The approach has been effectively used to identify ACOP in pharmaceutical pills because AgO nanoparticles demonstrate good stability, reproducibility, and repeatability.</p>\",\"PeriodicalId\":731,\"journal\":{\"name\":\"Physics of the Solid State\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2024-09-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physics of the Solid State\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1063783424600638\",\"RegionNum\":4,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHYSICS, CONDENSED MATTER\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physics of the Solid State","FirstCategoryId":"101","ListUrlMain":"https://link.springer.com/article/10.1134/S1063783424600638","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHYSICS, CONDENSED MATTER","Score":null,"Total":0}
引用次数: 0

摘要

摘要 如今,肝毒性化合物的鉴定对于临床诊断及其药物制剂的数量管理十分必要。本研究采用氧化银修饰的玻璃碳电极,利用茵芋叶提取物合成,用于检测(N-(4-羟基苯基)乙酰胺)。这种药物分子是常用的止痛剂,在特定条件下可能会对肝脏造成损伤。此外,还利用适当的表征技术研究了生物合成的氧化银纳米粒子的理化性质。通过 XRD 结构分析对氧化银的结晶特性进行了非破坏性检测。结构分析表明,Ocimum tenuiflorum 的生物成分有效地控制了金属离子氧化银的形成。傅立叶变换红外光谱(FT-IR)的振动赋值表明,氧化银纳米粒子表面受到某些植物化合物的影响。此外,颗粒的整体均匀性及其分布也在很大程度上受到生物大分子的控制。在 0.1 M H2SO4 中氧化(N-(4-羟基苯基)乙酰胺)时,与裸 SPE 相比,AgO NPs 表现出更优越的电催化活性,分离的氧化峰电位允许同时检测目标物,线性范围从 5 × 10-6 到 3.4 × 10-6 mol L-1 不等,检测限低至 8.5 × 10-6 mol L-1,精度和准确度出色(S/N = 3)。由于 AgO 纳米粒子具有良好的稳定性、再现性和重复性,该方法已被有效地用于鉴定药丸中的 ACOP。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Biogenic Silver Oxide Nanoparticles for Enhanced Electrochemical (N-(4-Hydroxyphenyl)Acetamide) Sensing

Biogenic Silver Oxide Nanoparticles for Enhanced Electrochemical (N-(4-Hydroxyphenyl)Acetamide) Sensing

Biogenic Silver Oxide Nanoparticles for Enhanced Electrochemical (N-(4-Hydroxyphenyl)Acetamide) Sensing

Nowadays, the identification of hepatotoxic compounds is necessary for clinical diagnosis as well as quantity management of their pharmaceutical formulations. In this study, silver oxide modified glassy carbon electrode synthesized using leaf extract of Ocimum tenuiflorum is adopted for sensing of (N-(4-hydroxyphenyl)acetamide). This drug molecules has regularly used pain killer that might cause liver injury under specific conditions. In addition, their physiochemical properties of bio-synthesized AgO nanoparticles have been examined with appropriate characterization techniques. Crystalline characteristic of AgO was non-destructively examined by the XRD-structural analysis. Structural examination claimed that the bioconstitutents of Ocimum tenuiflorum was effectively governs silver oxide formations from metal ions. The FT-IR vibrational assignments illustrate the AgO nanoparticles surface was influenced by some of the phytocompounds. Moreover, the overall particle’s uniformity and their distribution has been considerably controlled by the biomolecules. When oxidizing (N-(4-hydroxyphenyl)acetamide) in 0.1 M H2SO4, AgO NPs demonstrated superior electrocatalytic activity compared to bare SPE, and the separated oxidation peak potentials permitted simultaneous detection of the targets with broad linear ranges from 5 × 10–6 to 3.4 × 10–6 mol L–1 low detection limit 8.5 × 10–6 mol L–1, and outstanding precision and accuracy (S/N = 3). The approach has been effectively used to identify ACOP in pharmaceutical pills because AgO nanoparticles demonstrate good stability, reproducibility, and repeatability.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Physics of the Solid State
Physics of the Solid State 物理-物理:凝聚态物理
CiteScore
1.70
自引率
0.00%
发文量
60
审稿时长
2-4 weeks
期刊介绍: Presents the latest results from Russia’s leading researchers in condensed matter physics at the Russian Academy of Sciences and other prestigious institutions. Covers all areas of solid state physics including solid state optics, solid state acoustics, electronic and vibrational spectra, phase transitions, ferroelectricity, magnetism, and superconductivity. Also presents review papers on the most important problems in solid state physics.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信