{"title":"蚯蚓躯体运动肌肉中 Ca2+ 传感器蛋白的免疫荧光定位","authors":"L. F. Nurullin, N. D. Almazov, E. M. Volkov","doi":"10.1134/s0022093024040045","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>Immunofluorescent labeling revealed calmodulin, Ca<sup>2+</sup>/calmodulin-dependent\nprotein kinases I and II, synaptotagmin II and VII, and calcineurin\nA in somatic motor muscles of the earthworm <i>Lumbricus terrestris</i>.\nThese Ca<sup>2+</sup> sensor proteins are detected\nin both synaptic and extrasynaptic regions. However, synaptotagmin\nII and VII, as well as calcineurin A, are mainly localized in the\narea of neuromuscular junctions, with the synaptic localization\nfor synaptotagmin VII and calcineurin A being pronounced most distinctly.</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"68 1","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Immunofluorescent Localization of Ca2+ Sensor Proteins in Somatic Motor Muscles of the Earthworm Lumbricus terrestris\",\"authors\":\"L. F. Nurullin, N. D. Almazov, E. M. Volkov\",\"doi\":\"10.1134/s0022093024040045\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<h3 data-test=\\\"abstract-sub-heading\\\">Abstract</h3><p>Immunofluorescent labeling revealed calmodulin, Ca<sup>2+</sup>/calmodulin-dependent\\nprotein kinases I and II, synaptotagmin II and VII, and calcineurin\\nA in somatic motor muscles of the earthworm <i>Lumbricus terrestris</i>.\\nThese Ca<sup>2+</sup> sensor proteins are detected\\nin both synaptic and extrasynaptic regions. However, synaptotagmin\\nII and VII, as well as calcineurin A, are mainly localized in the\\narea of neuromuscular junctions, with the synaptic localization\\nfor synaptotagmin VII and calcineurin A being pronounced most distinctly.</p>\",\"PeriodicalId\":15805,\"journal\":{\"name\":\"Journal of Evolutionary Biochemistry and Physiology\",\"volume\":\"68 1\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2024-08-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Evolutionary Biochemistry and Physiology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1134/s0022093024040045\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Evolutionary Biochemistry and Physiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1134/s0022093024040045","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
摘要免疫荧光标记显示,钙调蛋白、Ca2+/钙调蛋白依赖蛋白激酶Ⅰ和Ⅱ、突触位点蛋白Ⅱ和Ⅶ以及钙调素A存在于蚯蚓的躯体运动肌肉中。然而,突触位点蛋白 II 和 VII 以及钙调素 A 主要定位在神经肌肉接头区域,其中突触位点蛋白 VII 和钙调素 A 的突触定位最为明显。
Immunofluorescent Localization of Ca2+ Sensor Proteins in Somatic Motor Muscles of the Earthworm Lumbricus terrestris
Abstract
Immunofluorescent labeling revealed calmodulin, Ca2+/calmodulin-dependent
protein kinases I and II, synaptotagmin II and VII, and calcineurin
A in somatic motor muscles of the earthworm Lumbricus terrestris.
These Ca2+ sensor proteins are detected
in both synaptic and extrasynaptic regions. However, synaptotagmin
II and VII, as well as calcineurin A, are mainly localized in the
area of neuromuscular junctions, with the synaptic localization
for synaptotagmin VII and calcineurin A being pronounced most distinctly.
期刊介绍:
Journal of Evolutionary Biochemistry and Physiology publishes original experimental and theoretical and review articles related to evolution of the main forms of metabolism in connection with life origin; comparative and ontogenetic physiology and biochemistry, biochemical evolution of animal world; as well as evolution of functions; morphology, pharmacology, pathophysiology and ecological physiology. The journal welcomes manuscripts from all countries in the English or Russian language.