低密度脂蛋白胆固醇：这都是好消息吗？

IF 5.7 2区医学 Q1 PERIPHERAL VASCULAR DISEASE

Current Atherosclerosis Reports Pub Date : 2024-09-10 DOI:10.1007/s11883-024-01238-y

Jacob Hartz

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引用次数: 0

摘要

最近的研究结果越来越多的文献表明，较低的低密度脂蛋白胆固醇水平与心血管疾病风险的降低有关。此外，使用药物达到这些水平是非常安全的。虽然他汀类药物可能会略微增加糖尿病和出血性中风的风险，但其益处大于风险。总结虽然专业协会的建议越来越积极，但如果设定更高的低密度脂蛋白胆固醇目标，还可以进一步降低风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Low LDL-C: Is It all Good News?

Purpose of review

This review presents the risks and benefits of very low LDL cholesterol and the safety of using lipid-lowering therapy to achieve these levels.

Recent findings

A growing body of literature suggests that lower LDL cholesterol levels are associated with a reduced risk of cardiovascular disease. Further, achieving these levels with pharmaceuticals is remarkably safe. Although statins may slightly increase the risk of diabetes mellitus and hemorrhagic stroke, the benefits outweigh the risks.

Summary

While recommendations from professional societies are increasingly aggressive, additional risk reduction could be achieved by setting more even ambitious LDL cholesterol goals.

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来源期刊

Current Atherosclerosis Reports 医学-

CiteScore

9.00

自引率

3.40%

发文量

审稿时长

6-12 weeks

期刊介绍： The aim of this journal is to systematically provide expert views on current basic science and clinical advances in the field of atherosclerosis and highlight the most important developments likely to transform the field of cardiovascular prevention, diagnosis, and treatment. We accomplish this aim by appointing major authorities to serve as Section Editors who select leading experts from around the world to provide definitive reviews on key topics and papers published in the past year. We also provide supplementary reviews and commentaries from well-known figures in the field. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.