通过方差数量性状位点改进维生素 D 基因与环境相互作用的特征描述

medRxiv - Genetic and Genomic Medicine Pub Date : 2024-08-31 DOI:10.1101/2024.08.30.24312868

Tianyuan Lu, Wenmin Zhang, Cassianne Robinson-Cohen, Corinne D. Engelman, Qiongshi Lu, Ian H. de Boer, Lei Sun, Andrew D. Paterson

{"title":"通过方差数量性状位点改进维生素 D 基因与环境相互作用的特征描述","authors":"Tianyuan Lu, Wenmin Zhang, Cassianne Robinson-Cohen, Corinne D. Engelman, Qiongshi Lu, Ian H. de Boer, Lei Sun, Andrew D. Paterson","doi":"10.1101/2024.08.30.24312868","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Understanding gene-environment interaction effects influencing vitamin D status may refine nutrition and public health strategies for vitamin D deficiency. Recent methodological advances have enabled the identification of variance quantitative trait loci (vQTLs) where gene-environment interaction effects are enriched.","PeriodicalId":501375,"journal":{"name":"medRxiv - Genetic and Genomic Medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Improved characterization of gene-environment interactions for vitamin D through variance quantitative trait loci\",\"authors\":\"Tianyuan Lu, Wenmin Zhang, Cassianne Robinson-Cohen, Corinne D. Engelman, Qiongshi Lu, Ian H. de Boer, Lei Sun, Andrew D. Paterson\",\"doi\":\"10.1101/2024.08.30.24312868\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<strong>Background</strong> Understanding gene-environment interaction effects influencing vitamin D status may refine nutrition and public health strategies for vitamin D deficiency. Recent methodological advances have enabled the identification of variance quantitative trait loci (vQTLs) where gene-environment interaction effects are enriched.\",\"PeriodicalId\":501375,\"journal\":{\"name\":\"medRxiv - Genetic and Genomic Medicine\",\"volume\":\"47 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-08-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Genetic and Genomic Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.08.30.24312868\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Genetic and Genomic Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.08.30.24312868","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

背景了解影响维生素 D 状态的基因-环境互作效应可完善针对维生素 D 缺乏症的营养和公共卫生策略。近年来方法学的进步使得基因与环境互作效应富集的变异数量性状位点（vQTLs）的鉴定成为可能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Improved characterization of gene-environment interactions for vitamin D through variance quantitative trait loci

Background Understanding gene-environment interaction effects influencing vitamin D status may refine nutrition and public health strategies for vitamin D deficiency. Recent methodological advances have enabled the identification of variance quantitative trait loci (vQTLs) where gene-environment interaction effects are enriched.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

medRxiv - Genetic and Genomic Medicine

自引率

0.00%

发文量