死后冠状动脉计算机断层扫描血管造影的钙化减影法

IF 2.2 3区 医学 Q1 MEDICINE, LEGAL
Go Inokuchi, Masatoshi Kojima, Fumiko Chiba, Yumi Hoshioka, Maiko Yoshida, Shigeki Tsuneya, Hirotaro Iwase
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引用次数: 0

摘要

虽然冠状动脉计算机断层扫描(CT)血管造影术是评估死前和死后冠状动脉病变的有效工具,但当存在高度钙化的病变时,很难对管腔进行准确评估,原因是开花和部分容积伪影会导致高估狭窄程度。在临床实践中,为了克服这一诊断问题,人们设计了一种减影方法,通过从对比图像中减去对比前图像来去除钙化。在本报告中,我们介绍了一种利用图像分析软件对死后冠状动脉 CT 血管造影进行钙化减影的方法。这种方法是根据初步实验结果而设计的,实验结果表明,使用较窄视野和骨核重建的图像可以获得更高的空间分辨率,从而实现最精确的减影。这种减影方法可以在对比增强图像上评估管腔的通畅度和狭窄程度,并使用实际标本进行验证,在实际标本中,由于钙化严重,很难对管腔进行评估。结果在形态上与宏观检查结果相似。这种方法可以更快速、更可靠地检索病变,有望在法医实践中用于死后冠状动脉造影。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A calcification subtraction method for postmortem coronary computed tomography angiography

A calcification subtraction method for postmortem coronary computed tomography angiography

Although coronary computed tomography (CT) angiography is a useful tool for evaluating coronary artery lesions both ante- and postmortem, accurate evaluation of the lumen is difficult when highly calcified lesions are present, owing to overestimation of stenosis caused by blooming and partial volume artifacts. In clinical practice, to overcome this diagnostic problem, a subtraction method has been devised to remove calcification by subtracting the precontrast image from the contrast image. In this report, we describe a calcification subtraction method using image analysis software for postmortem coronary CT angiography. This method was devised based on preliminary experimental results showing that the most accurate subtraction was achieved using images reconstructed with a narrower field of view and bone kernel, resulting in higher spatial resolution. This subtraction method allowed evaluation of lumen patency and the degree of stenosis on contrast-enhanced images in a verification using actual specimens where evaluation of the lumen had been difficult because of high calcification. The results were morphologically similar to the macroscopic findings. This method allows more rapid and reliable lesion retrieval and is expected to be useful for postmortem coronary angiography in forensic practice.

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来源期刊
CiteScore
5.80
自引率
9.50%
发文量
165
审稿时长
1 months
期刊介绍: The International Journal of Legal Medicine aims to improve the scientific resources used in the elucidation of crime and related forensic applications at a high level of evidential proof. The journal offers review articles tracing development in specific areas, with up-to-date analysis; original articles discussing significant recent research results; case reports describing interesting and exceptional examples; population data; letters to the editors; and technical notes, which appear in a section originally created for rapid publication of data in the dynamic field of DNA analysis.
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