增强现实导航系统(SIRIO)用于椎体肿瘤消融术中的神经损伤治疗

IF 2.8 4区 医学 Q2 ONCOLOGY
Eliodoro Faiella, Rebecca Casati, Matteo Pileri, Giuseppina Pacella, Carlo Altomare, Elva Vergantino, Amalia Bruno, Bruno Beomonte Zobel, Rosario Francesco Grasso
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引用次数: 0

摘要

(1)本研究评估了CT引导下的SIRIO增强现实导航系统对原发性和转移性骨肿瘤椎体热消融(RTA)手术疗效和神经保护临床结果的影响。(2)方法:对28例椎体RTA手术进行了回顾性非随机分析,比较了12例SIRIO辅助手术和16例非SIRIO辅助手术。主要结果包括剂量-长度乘积(DLP)和硬膜外剥离时间。次要结果包括技术成功率、并发症发生率以及手术时间(VAS 时间 0)和术后三个月(VAS 时间 1)的疼痛评分。统计分析包括 t 检验、曼-惠特尼 U 检验和多元回归。(3) 结果:与非 SIRIO 辅助手术相比,SIRIO 辅助手术显著减少了 DLP(307.42 mGycm vs. 460.31 mGycm,p = 2.23 × 10-8)和手术硬膜外剥离时间(13.48 分钟 vs. 32.26 分钟,p = 2.61 × 10-12)。多元回归证实了这些减少是显著的(DLP:β = -162.38, p < 0.001;时间:β = -18.25,p < 0.001)。疼痛评分(VAS 时间 1)在组间无明显差异,肿瘤类型对结果无明显影响。(4) 结论:SIRIO 系统提高了神经保护的有效性和安全性,减少了脊柱肿瘤消融过程中的辐射剂量和手术时间,同时保持了一致的疼痛治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Augmented Reality Navigation System (SIRIO) for Neuroprotecion in Vertebral Tumoral Ablation
(1) This study evaluates the impact of the CT-guided SIRIO augmented reality navigation system on the procedural efficacy and clinical outcomes of neuroprotection in vertebral thermal ablation (RTA) for primary and metastatic bone tumors. (2) Methods: A retrospective non-randomized analysis of 28 vertebral RTA procedures was conducted, comparing 12 SIRIO-assisted and 16 non-SIRIO-assisted procedures. The primary outcomes included dose-length product (DLP) and epidural dissection time. The secondary outcomes included technical success, complication rates, and pain scores at procedural time (VAS Time 0) and three months post-procedure (VAS Time 1). The statistical analyses included t-tests, Mann–Whitney U tests, and multiple regression. (3) Results: SIRIO-assisted procedures significantly reduced DLP (307.42 mGycm vs. 460.31 mGycm, p = 2.23 × 10−8) and procedural epidural dissection time (13.48 min vs. 32.26 min, p = 2.61 × 10−12) compared to non-SIRIO-assisted procedures. Multiple regression confirmed these reductions were significant (DLP: β = −162.38, p < 0.001; time: β = −18.25, p < 0.001). Pain scores (VAS Time 1) did not differ significantly between groups, and tumor type did not significantly influence outcomes. (4) Conclusions: The SIRIO system enhances neuroprotection efficacy and safety, reducing radiation dose and procedural time during spine tumoral ablation while maintaining consistent pain management outcomes.
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来源期刊
Current oncology
Current oncology ONCOLOGY-
CiteScore
3.30
自引率
7.70%
发文量
664
审稿时长
1 months
期刊介绍: Current Oncology is a peer-reviewed, Canadian-based and internationally respected journal. Current Oncology represents a multidisciplinary medium encompassing health care workers in the field of cancer therapy in Canada to report upon and to review progress in the management of this disease. We encourage submissions from all fields of cancer medicine, including radiation oncology, surgical oncology, medical oncology, pediatric oncology, pathology, and cancer rehabilitation and survivorship. Articles published in the journal typically contain information that is relevant directly to clinical oncology practice, and have clear potential for application to the current or future practice of cancer medicine.
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