Jin-Zhi Zhang, Xiao-Zhen Song, Xiao-Na Song, Ya-Lin Shen, Hong Tang, Hong Li
{"title":"炎症性肠病患者睡眠障碍的患病率和风险因素:一项横断面研究","authors":"Jin-Zhi Zhang, Xiao-Zhen Song, Xiao-Na Song, Ya-Lin Shen, Hong Tang, Hong Li","doi":"10.1007/s00384-024-04712-w","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background</h3><p>Sleep disorders are one of the major public health problems, which can potentially induce inflammation and exacerbate disease activity, resulting in compromised sleep quality. This study aimed to investigate the prevalence and risk factors associated with sleep disorders among patients with inflammatory bowel disease (IBD).</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>Between March 2023 and February 2024, the Pittsburgh Sleep Quality Index was employed to assess sleep quality in both IBD patients and healthy control subjects. Univariate and multivariate analysis were performed to identify the risk factors associated with SD in IBD patients.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Overall, 208 IBD patients [150 Crohn’s disease (CD) and 58 ulcerative colitis (UC)] and 199 healthy individuals were included. Sleep disorders were observed in 59.6% of patients with IBD, with a higher prevalence among females (63.5%) compared to males (56.9%) (<i>P</i> = 0.476). The prevalence of sleep disorders in IBD patients was significantly higher than that found in healthy controls (37.7%) (all <i>P</i> < 0.01). The prevalence of sleep disorders among CD and UC patients was 58% and 63.8%, respectively (<i>P</i> = 0.291). The multivariate analysis revealed that older age (<i>OR</i>, 1.070; 95% <i>CI</i>: 1.035–1.105, <i>P</i> = 0.000), smoking (<i>OR</i>, 2.698; 95% <i>CI</i>: 1.089–6.685, <i>P</i> = 0.032), and depression (<i>OR</i>, 4.779; 95% <i>CI</i>: 1.915–11.928, <i>P</i> = 0.001) were risk factors for sleep disorders in IBD patients. However, higher body mass index (<i>OR</i>, 0.879; 95% <i>CI</i>: 0.790–0.977, <i>P</i> = 0.017) was identified as a protective factor.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Sleep disorders are common among IBD patients regardless of activity levels. Smoking and depression are the major risk factors.</p>","PeriodicalId":13789,"journal":{"name":"International Journal of Colorectal Disease","volume":"35 1","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalence and risk factors of sleep disorders in inflammatory bowel disease: a cross-sectional study\",\"authors\":\"Jin-Zhi Zhang, Xiao-Zhen Song, Xiao-Na Song, Ya-Lin Shen, Hong Tang, Hong Li\",\"doi\":\"10.1007/s00384-024-04712-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<h3 data-test=\\\"abstract-sub-heading\\\">Background</h3><p>Sleep disorders are one of the major public health problems, which can potentially induce inflammation and exacerbate disease activity, resulting in compromised sleep quality. This study aimed to investigate the prevalence and risk factors associated with sleep disorders among patients with inflammatory bowel disease (IBD).</p><h3 data-test=\\\"abstract-sub-heading\\\">Methods</h3><p>Between March 2023 and February 2024, the Pittsburgh Sleep Quality Index was employed to assess sleep quality in both IBD patients and healthy control subjects. Univariate and multivariate analysis were performed to identify the risk factors associated with SD in IBD patients.</p><h3 data-test=\\\"abstract-sub-heading\\\">Results</h3><p>Overall, 208 IBD patients [150 Crohn’s disease (CD) and 58 ulcerative colitis (UC)] and 199 healthy individuals were included. Sleep disorders were observed in 59.6% of patients with IBD, with a higher prevalence among females (63.5%) compared to males (56.9%) (<i>P</i> = 0.476). The prevalence of sleep disorders in IBD patients was significantly higher than that found in healthy controls (37.7%) (all <i>P</i> < 0.01). The prevalence of sleep disorders among CD and UC patients was 58% and 63.8%, respectively (<i>P</i> = 0.291). The multivariate analysis revealed that older age (<i>OR</i>, 1.070; 95% <i>CI</i>: 1.035–1.105, <i>P</i> = 0.000), smoking (<i>OR</i>, 2.698; 95% <i>CI</i>: 1.089–6.685, <i>P</i> = 0.032), and depression (<i>OR</i>, 4.779; 95% <i>CI</i>: 1.915–11.928, <i>P</i> = 0.001) were risk factors for sleep disorders in IBD patients. However, higher body mass index (<i>OR</i>, 0.879; 95% <i>CI</i>: 0.790–0.977, <i>P</i> = 0.017) was identified as a protective factor.</p><h3 data-test=\\\"abstract-sub-heading\\\">Conclusion</h3><p>Sleep disorders are common among IBD patients regardless of activity levels. 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Prevalence and risk factors of sleep disorders in inflammatory bowel disease: a cross-sectional study
Background
Sleep disorders are one of the major public health problems, which can potentially induce inflammation and exacerbate disease activity, resulting in compromised sleep quality. This study aimed to investigate the prevalence and risk factors associated with sleep disorders among patients with inflammatory bowel disease (IBD).
Methods
Between March 2023 and February 2024, the Pittsburgh Sleep Quality Index was employed to assess sleep quality in both IBD patients and healthy control subjects. Univariate and multivariate analysis were performed to identify the risk factors associated with SD in IBD patients.
Results
Overall, 208 IBD patients [150 Crohn’s disease (CD) and 58 ulcerative colitis (UC)] and 199 healthy individuals were included. Sleep disorders were observed in 59.6% of patients with IBD, with a higher prevalence among females (63.5%) compared to males (56.9%) (P = 0.476). The prevalence of sleep disorders in IBD patients was significantly higher than that found in healthy controls (37.7%) (all P < 0.01). The prevalence of sleep disorders among CD and UC patients was 58% and 63.8%, respectively (P = 0.291). The multivariate analysis revealed that older age (OR, 1.070; 95% CI: 1.035–1.105, P = 0.000), smoking (OR, 2.698; 95% CI: 1.089–6.685, P = 0.032), and depression (OR, 4.779; 95% CI: 1.915–11.928, P = 0.001) were risk factors for sleep disorders in IBD patients. However, higher body mass index (OR, 0.879; 95% CI: 0.790–0.977, P = 0.017) was identified as a protective factor.
Conclusion
Sleep disorders are common among IBD patients regardless of activity levels. Smoking and depression are the major risk factors.
期刊介绍:
The International Journal of Colorectal Disease, Clinical and Molecular Gastroenterology and Surgery aims to publish novel and state-of-the-art papers which deal with the physiology and pathophysiology of diseases involving the entire gastrointestinal tract. In addition to original research articles, the following categories will be included: reviews (usually commissioned but may also be submitted), case reports, letters to the editor, and protocols on clinical studies.
The journal offers its readers an interdisciplinary forum for clinical science and molecular research related to gastrointestinal disease.