{"title":"食物诱发的狗甲状腺毒症","authors":"Marco Isidori, Ronald J. Corbee, Hans S. Kooistra","doi":"10.1002/vrc2.975","DOIUrl":null,"url":null,"abstract":"This report presents a case of factitial thyrotoxicosis in a dog ensuing from the long‐term administration of a raw meat‐based pet food adulterated with thyroid tissue. A 7‐year‐old, male, neutered bull terrier was brought to the clinic because of polyuria/polydipsia, restlessness and a decrease in bodyweight despite increased appetite. Physical examination revealed hyperthermia, polypnea, tachycardia and a mild underconditioning, whereas routine bloodwork and urinalysis were unremarkable. Exogenous thyrotoxicosis was suspected based on thyroid function test results, together with contrast computed tomography and nuclear scintigraphy of the thyroid gland, showing increased serum T4 concentrations and very low thyroid‐stimulating hormone concentration in the absence of either eutopic or ectopic thyroid tumours. Histological and biomedical analyses of the dog's diet identified it to be the likely source of environmental thyroid hormones. Diagnosis confirmation was achieved by transitioning the dog to a new food, which was accompanied by a speedy and full remission of clinical signs.","PeriodicalId":23496,"journal":{"name":"Veterinary Record Case Reports","volume":"33 1","pages":""},"PeriodicalIF":0.3000,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Food‐induced thyrotoxicosis in a dog\",\"authors\":\"Marco Isidori, Ronald J. Corbee, Hans S. Kooistra\",\"doi\":\"10.1002/vrc2.975\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This report presents a case of factitial thyrotoxicosis in a dog ensuing from the long‐term administration of a raw meat‐based pet food adulterated with thyroid tissue. A 7‐year‐old, male, neutered bull terrier was brought to the clinic because of polyuria/polydipsia, restlessness and a decrease in bodyweight despite increased appetite. Physical examination revealed hyperthermia, polypnea, tachycardia and a mild underconditioning, whereas routine bloodwork and urinalysis were unremarkable. Exogenous thyrotoxicosis was suspected based on thyroid function test results, together with contrast computed tomography and nuclear scintigraphy of the thyroid gland, showing increased serum T4 concentrations and very low thyroid‐stimulating hormone concentration in the absence of either eutopic or ectopic thyroid tumours. Histological and biomedical analyses of the dog's diet identified it to be the likely source of environmental thyroid hormones. Diagnosis confirmation was achieved by transitioning the dog to a new food, which was accompanied by a speedy and full remission of clinical signs.\",\"PeriodicalId\":23496,\"journal\":{\"name\":\"Veterinary Record Case Reports\",\"volume\":\"33 1\",\"pages\":\"\"},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2024-08-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Veterinary Record Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/vrc2.975\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary Record Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/vrc2.975","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
This report presents a case of factitial thyrotoxicosis in a dog ensuing from the long‐term administration of a raw meat‐based pet food adulterated with thyroid tissue. A 7‐year‐old, male, neutered bull terrier was brought to the clinic because of polyuria/polydipsia, restlessness and a decrease in bodyweight despite increased appetite. Physical examination revealed hyperthermia, polypnea, tachycardia and a mild underconditioning, whereas routine bloodwork and urinalysis were unremarkable. Exogenous thyrotoxicosis was suspected based on thyroid function test results, together with contrast computed tomography and nuclear scintigraphy of the thyroid gland, showing increased serum T4 concentrations and very low thyroid‐stimulating hormone concentration in the absence of either eutopic or ectopic thyroid tumours. Histological and biomedical analyses of the dog's diet identified it to be the likely source of environmental thyroid hormones. Diagnosis confirmation was achieved by transitioning the dog to a new food, which was accompanied by a speedy and full remission of clinical signs.
期刊介绍:
Vet Record Case Reports is an online resource that publishes articles in all fields of veterinary medicine and surgery so that veterinary professionals, researchers and others can easily find important information on both common and rare conditions. Articles may be about a single animal, herd, flock or other group of animals managed together. Common cases that present a diagnostic, ethical or management challenge, or that highlight aspects of mechanisms of injury, pharmacology or histopathology are deemed of particular educational value. All articles are peer reviewed and copy edited before publication.